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Record W2954818509 · doi:10.1002/cpt.1471

Educating the Next Generation of Pharmacogenomics Experts: Global Educational Needs and Concepts

2019· article· en· W2954818509 on OpenAlexaboutno aff
Katja S. Just, Richard M. Turner, Vita Dolžan, Erika Cecchin, Jesse J. Swen, David Gurwitz, Julia Stingl

Bibliographic record

VenueClinical Pharmacology & Therapeutics · 2019
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacogenetics and Drug Metabolism
Canadian institutionsnot available
FundersHorizon 2020 Framework ProgrammeMedical Research CouncilNational Institute for Health and Care ResearchEuropean CommissionBundesinstitut für Arzneimittel und Medizinprodukte
KeywordsPharmacogenomicsAgency (philosophy)HarmonizationRegulatory scienceSpecialtyPrecision medicineMedical educationMedicineFamily medicinePharmacologySociology

Abstract

fetched live from OpenAlex

Despite being a well-established research discipline, pharmacogenomics (PGx) is not yet routinely applied in patient care.Education is a crucial step for the successful implementation of PGx into the clinic.We need to offer collaborative, interprofessional approaches that encourage learning about PGx on an international level.It is especially important that PGx education enables the development of one's own thoughts and ideas to be able to understand and implement this rapidly developing field of science.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.048
metaresearch head score (Gemma)0.049
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.048
Threshold uncertainty score0.254

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0480.049
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0060.009
Scholarly communication0.0130.029
Open science0.0030.022
Research integrity0.0130.018
Insufficient payload (model declined to judge)0.0190.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.395
GPT teacher head0.553
Teacher spread0.158 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations38
Published2019
Admission routes1
Has abstractyes

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