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Record W2955346378 · doi:10.1038/s41379-019-0313-x

PAX8–GLIS3 gene fusion is a pathognomonic genetic alteration of hyalinizing trabecular tumors of the thyroid

2019· article· en· W2955346378 on OpenAlexaff
Caterina Marchiò, Arnaud Da Cruz Paula, Rodrigo Gularte‐Mérida, Thais Basili, Alissa Brandes, Edaise M. da Silva, Catarina Silveira, Lorenzo Ferrando, Jasna Metović, Francesca Maletta, Laura Annaratone, Fresia Pareja, Brian P. Rubin, Aaron P. Hoschar, Gaetano De Rosa, Stefano La Rosa, Massimo Bongiovanni, Bibianna Purgina, Simonetta Piana, Marco Volante, Britta Weigelt, Jorge S. Reis‐Filho, Mauro Papotti

Bibliographic record

VenueModern Pathology · 2019
Typearticle
Languageen
FieldMedicine
TopicThyroid Cancer Diagnosis and Treatment
Canadian institutionsOttawa Hospital
FundersNational Cancer InstituteNational Institutes of HealthUniversità degli Studi di TorinoFondazione Umberto VeronesiMinistero dell’Istruzione, dell’Università e della RicercaAssociazione Italiana per la Ricerca sul CancroDipartimenti di EccellenzaBreast Cancer Research Foundation
KeywordsPathognomonicPathologyBiologyFusion geneThyroidMedicineAnatomyGeneGeneticsDisease

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.353
Threshold uncertainty score0.421

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.237
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations60
Published2019
Admission routes1
Has abstractno

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