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Record W2959180649 · doi:10.3389/fneur.2019.00726

Measurement Variability Following MRI System Upgrade

2019· article· en· W2959180649 on OpenAlexafffund
Olivier Potvin, April Khademi, Isabelle Chouinard, Farnaz Farokhian, Louis Dieumegarde, Ilana R. Leppert, Rick Hoge, Maria Natasha Rajah, Pierre Bellec, Simon Duchesne

Bibliographic record

VenueFrontiers in Neurology · 2019
Typearticle
Languageen
FieldMedicine
TopicAdvanced MRI Techniques and Applications
Canadian institutionsUniversité LavalUniversité de MontréalInstitut Universitaire de Gériatrie de MontréalToronto Metropolitan UniversityMontreal Neurological Institute and HospitalDouglas Mental Health University InstituteMcGill University
FundersFonds de Recherche du Québec - SantéCanadian Institutes of Health ResearchPfizer CanadaAlzheimer's SocietyConsortium canadien en neurodégénérescence associée au vieillissementPfizer
KeywordsUpgradeMagnetic resonance imagingMedicineComputer scienceRadiology

Abstract

fetched live from OpenAlex

Major hardware/software changes to MRI platforms, either planned or unplanned, will almost invariably occur in longitudinal studies. Our objective was to assess the resulting variability on relevant imaging measurements in such context, specifically for three Siemens Healthcare Magnetom Trio upgrades to the Prismafit platform. We report data acquired on three healthy volunteers scanned before and after three different platform upgrades. We assessed differences in image signal (contrast-to-noise ratio (CNR)) on T1-weighted images (T1w) and fluid-attenuated inversion recovery images (FLAIR); brain morphometry on T1w image; and small vessel disease (white matter hyperintensities; WMH) on FLAIR image. The results show that for T1w images, the Prismafit upgrade increased the mean and variability of neocortical CNR, while for FLAIR images, no significant difference was observed. Larger volumes of white matter were observed after Prismafit upgrade and a significant relationship was observed between neocortical CNR and cortical volume. WMH were significantly smaller after Prismafit upgrade, when compared to results on the Magnetom Trio. Together, these results indicate that Prismafit upgrade significantly influenced image signal, brain morphometry measures and small vessel diseases measures and that these effects need to be taken into account when analyzing results from any longitudinal study undergoing similar changes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.723
Threshold uncertainty score0.379

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.253
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations36
Published2019
Admission routes2
Has abstractyes

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