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Record W2959639471 · doi:10.1053/j.gastro.2019.03.022

Canadian Association of Gastroenterology Clinical Practice Guideline for the Medical Management of Pediatric Luminal Crohn's Disease

2019· review· en· W2959639471 on OpenAlexafffundabout
David Mack, Eric I. Benchimol, Jeff Critch, Jennifer deBruyn, Frances Tse, Paul Moayyedi, Peter Church, Colette Deslandres, Wael El‐Matary, Hien Q. Huynh, Prévost Jantchou, Sally Lawrence, Anthony Otley, Mary Sherlock, Thomas D. Walters, Michael D. Kappelman, Daniel Sadowski, John K. Marshall, Anne M. Griffiths

Bibliographic record

VenueGastroenterology · 2019
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsRoyal Alexandra HospitalMcMaster Children's HospitalIWK FoundationUniversity of British ColumbiaHealth Sciences CentreCentre Hospitalier Universitaire Sainte-JustineHospital for Sick ChildrenMcMaster UniversityChildren's Hospital of Eastern OntarioPopulation Health Research InstituteUniversity of TorontoBC Children's HospitalMemorial University of NewfoundlandIzaak Walton Killam Health CentreStollery Children's HospitalAlberta Children's HospitalUniversity of CalgarySickKids FoundationAlberta Children’s Hospital FoundationUniversity of Ottawa
FundersJanssen CanadaEuropean Investment BankCanadian Institutes of Health ResearchAbbVie CanadaTakeda CanadaPfizer CanadaCrohn's and Colitis CanadaAstellas Pharma CanadaAllerganAbbVieTakeda Pharmaceutical CompanyAstraZeneca CanadaShireCanadian Child Health Clinician Scientist ProgramInstitute of Nutrition, Metabolism and DiabetesCanadian Association of GastroenterologyCelgeneGlaxoSmithKline
KeywordsMedicineMaintenance therapyThiopurine methyltransferaseGuidelineDiseaseInternal medicinePediatric gastroenterologyAzathioprineBudesonideCrohn's diseaseMethotrexateVedolizumabInflammatory bowel diseaseConcomitantIntensive care medicineChemotherapyCorticosteroidPathology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.994
Threshold uncertainty score0.268

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0050.005
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0030.001
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0060.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.347
Teacher spread0.326 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations73
Published2019
Admission routes3
Has abstractno

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