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Pre-eclampsia: pathophysiology and clinical implications

2019· review· en· 1,219 citations· W2960659672 on OpenAlex· 10.1136/bmj.l2381

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
ObservationalSystematic reviewTheoretical or conceptualNot applicable
Classifier consensus
ObservationalNot applicable
Teacher imitation scores

Codex

Not applicable0.452
Systematic review0.102
Other design0.054
Observational0.043
Metaresearch0.008
Meta-analysis0.001
Research integrity0.000
Meta-epidemiology (broad)0.000
Theoretical or conceptual0.000
Randomized trial0.000
Case report0.000
Non-randomized trial0.000
Meta-epidemiology (narrow)0.000
Bibliometrics0.000
Open science0.000
Science and technology studies0.000
Simulation or modelling0.000
Scholarly communication0.000
Bench or experimental0.000
Qualitative0.000

Gemma

Observational0.256
Not applicable0.233
Systematic review0.133
Theoretical or conceptual0.015
Meta-analysis0.003
Metaresearch0.001
Research integrity0.001
Meta-epidemiology (broad)0.000
Case report0.000
Non-randomized trial0.000
Simulation or modelling0.000
Randomized trial0.000
Meta-epidemiology (narrow)0.000
Bibliometrics0.000
Science and technology studies0.000
Open science0.000
Scholarly communication0.000
Qualitative0.000
Bench or experimental0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.140
GPT teacher head0.461
Teacher spread
0.321 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical presentation is highly variable but hypertension and proteinuria are usually seen. These systemic signs arise from soluble factors released from the placenta as a result of a response to stress of syncytiotrophoblast. There are two sub-types: early and late onset pre-eclampsia, with others almost certainly yet to be identified. Early onset pre-eclampsia arises owing to defective placentation, whilst late…

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