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Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study

2019· article· en· 1,153 citations· W2963476376 on OpenAlex· 10.1016/s1470-2045(19)30388-2

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.048
GPT teacher head0.390
Teacher spread
0.342 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The Lancet Oncology
Topic
Cancer Immunotherapy and Biomarkers
Field
Medicine
Canadian institutions
Sunnybrook Health Science CentreHealth Sciences Centre
Funders
Merck Sharp and DohmeLes Laboratories Pierre FabreMerckMeso Scale DiagnosticsRocheBritish Microcirculation SocietyAmgen
Keywords
IpilimumabPembrolizumabPost-hoc analysisOpen labelMedicinePost hocOncologyInternal medicineClinical trialImmunotherapyCancer
Has abstract in OpenAlex
no