Capacity of an in vitro rat skin model to predict human dermal absorption: Influences of aging and anatomical site
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.
The three-model screen
all 1,000 screened works →All three models called this out of scope.
Evaluates an in vitro rat skin model's ability to predict human dermal absorption; a toxicology assay for a domain question.
It evaluates a skin model for predicting dermal absorption, not research practice.
Toxicology model predicting human dermal absorption; domain method validation, not research-on-research.
Abstract
No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
The record
- Venue
- Toxicology in Vitro
- Topic
- Contact Dermatitis and Allergies
- Field
- Medicine
- Canadian institutions
- —
- Funders
- Institut national de la recherche scientifique
- Keywords
- Human skinStratum corneumAbsorption (acoustics)ChemistryDorsumPenetration (warfare)In vitroChromatographyBiophysicsMaterials scienceAnatomyPathologyBiochemistryBiologyMedicine
- Has abstract in OpenAlex
- no