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Record W2968536677 · doi:10.1007/s00125-019-4967-1

Dysregulated expression but redundant function of the long non-coding RNA HOTAIR in diabetic kidney disease

2019· article· en· W2968536677 on OpenAlexafffund
Syamantak Majumder, Mitchell J. Hadden, Karina Thieme, Sri Nagarjun Batchu, Divya Niveditha, Shibasish Chowdhury, Veera Ganesh Yerra, Suzanne L. Advani, Bridgit B. Bowskill, Youan Liu, Hana Vakili, Tamadher A. Alghamdi, Kathryn White, Laurette Geldenhuys, Ferhan Siddiqi, Andrew Advani

Bibliographic record

VenueDiabetologia · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer-related molecular mechanisms research
Canadian institutionsDalhousie UniversitySt. Michael's Hospital
FundersCanadian Institutes of Health ResearchInstitute of Nutrition, Metabolism and DiabetesFundação de Amparo à Pesquisa do Estado de São PauloBanting and Best Diabetes Centre, University of TorontoKidney Foundation of CanadaDiabetes Canada
KeywordsHOTAIRLong non-coding RNADiseaseHuman physiologyDiabetes mellitusRNABiologyKidney diseaseMedicineFunction (biology)Cancer researchBioinformaticsGeneticsComputational biologyInternal medicineEndocrinologyGene

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.072
Threshold uncertainty score0.571

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.228
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations55
Published2019
Admission routes2
Has abstractno

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