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Record W2969494932 · doi:10.21836/pem20190205

Chronic gastric dilatation in horses: diagnosis, treatment and feeding management – A survey of 20 clinical cases

2019· article· en· W2969494932 on OpenAlexfundno aff
V Bäuerlein, Ingrid Vervuert, Monica Venner

Bibliographic record

VenuePferdeheilkunde Equine Medicine · 2019
Typearticle
Languageen
FieldVeterinary
TopicVeterinary Equine Medical Research
Canadian institutionsnot available
FundersMcGill UniversityAmerican Association of Equine Practitioners Foundation
KeywordsMedicineIntensive care medicineVeterinary medicineInternal medicine

Abstract

fetched live from OpenAlex

Chronic gastric dilatation is a rarely diagnosed disease of the horse. The objective of this report was to describe the clinical and ultrasonographic findings of 20 cases of chronic gastric dilatation in horses. Furthermore, horses' clinical history, signalment and clinical and gastroscopic findings were recorded. Medication, feeding management and outcome are presented. Inclusion criteria were: 1) Clinical signs of recurrent abdominal discomfort or resistance to the riders leg; 2a) Repeated ultrasonographic finding of an enlarged stomach (more than five intercostal spaces), or alternatively; 2b) Repeated gastroscopic finding of an impacted stomach in combination with a subsequent sonographical confirmation; 3a) No gastric emptying following 12 hours of starvation, or 3b) Emptying but repeated episodes of dilatation following normal feeding regime; 4) Exclusion of acute gastric impactions and other gastrointestinal disorders. All horses had shown one or several of the following symptoms: repeated signs of discomfort, recurrent mild or moderate acute colic, defensive reaction when fixing the girth or against the riders left leg, chronic weight loss, poor performance and more. With exception of the rectal examination, clinical and laboratory examination was not conclusive. 19 horses showed an enlarged stomach at initial sonography (range: six to eleven intercostal spaces). The initial examination in one horse referred to our clinic was merely by gastroscopy. Gastroscopy was performed in eleven cases. The horses were treated with metoclopramide hydrochloride ( 0.1-0.15 mg/kg twice daily p.o.) and feeding management was adapted according to nutritionist's or veterinarian's recommendations. The mean duration of treatment was 16 months at submission of the manuscript. No side effects were observed. Seventeen of the treated horses survived in the long term. One horse was euthanized 10 days after start of treatment with metoclopramide hydrochloride, at the request of the owner as he had noticed no clinical improvement in that period of time. Two horses were euthanized because of orthopedic problems. Fifteen horses showed complete, and four horses partial clinical improvement after treatment and feeding management was adapted. Metoclopramide hydrochloride seemed effective for the long-term treatment of chronic gastric dilatation. Long-term administration of metoclopramide hydrochloride could be an alternative to bethanechol. Further studies are needed to determine the exact pathophysiologic mechanisms of chronic gastric dilatation and to determine the exact diagnostic findings related to different disease states.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.101
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.231
GPT teacher head0.467
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2019
Admission routes1
Has abstractyes

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