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End to end QA in image guided and adaptive radiation therapy

2019· article· en· W2971322501 on OpenAlexaff
L J Schreiner

Bibliographic record

VenueJournal of Physics Conference Series · 2019
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsKingston Health Sciences CentreQueen's University
Fundersnot available
KeywordsEnd-to-end principleRadiation therapyComputer scienceMedical physicsImage (mathematics)Image-guided radiation therapyComputer visionArtificial intelligenceMedicineRadiologyMedical imaging

Abstract

fetched live from OpenAlex

Abstract It has been suggested that modern radiation therapy could benefit from adopting the “End to End” (E2E) type of testing developed originally in computer science to determine whether applications and systems work as required under real-world scenarios. The motivation for adopting E2E techniques for image guided adaptive radiation therapy validation is to extend beyond current common testing using standard physics QA that inherently probes only select points or systems within the IGART schema. E2E methodologies extend the testing to evaluate complete IGART processes, including the complex interchanges that occur during and throughout a patient’s treatment as clinical staff interpret and respond to information acquired during the treatment course. While limited radiotherapy E2E QA may have been adopted periodically by clinics when implementing a new treatment technique, clinical E2E QA has been confined to date mainly to tests mediated by external auditing bodies such as IROC, the Imaging and Radiation Oncology Core in the United States. This testing often includes having the clinic in question irradiate a purpose-built phantom containing dosimeters to specific criteria under protocols set by the auditing body. The auditors then determine off site whether the clinic’s treatment process was successful by comparing the dose measurements with the intended dose delivery. The advance of three dimensional (3D) radiation dosimeters opens the possibility for in-house E2E testing. Approaches for in-house E2E testing have been proposed for over a decade, but such comprehensive internal E2E testing has not been widely adopted. In this presentation the barriers and challenges to the development of clinical in-house E2E QA will be reviewed primarily based on the experience in Kingston.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.657
Threshold uncertainty score0.466

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.284
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2019
Admission routes1
Has abstractyes

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