Investigating a Role for BLADE-ON-PETIOLE Genes in Plant Defense
Bibliographic record
Abstract
Plants have evolved multiple layers of defense to ward off pathogens.Pathogen-associated molecular pattern (PAMPs)-triggered immunity (PTI) is the most ancient and basal form of plant defense.BLADE-ON-PETIOLE1/2 (BOP1/2) are members of an evolutionarily conserved subclade of BTB-ankyrin proteins that control plant development within the NON-EXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) family of plant defense regulators that control systemic acquired resistance.I analyzed the transcriptome of BOP1 overexpressing plants to find a previously undiscovered role for BOPs in plant defense.Gene Ontology analysis revealed that 35% of upregulated genes belong to plant defense pathways with PTI forming the largest group.Among these PTI genes were clade I TGA factors, also essential for BOP-mediated developmental processes.Data validation and direct pathogen testing support the model that BOPs and clade I TGAs co-regulate a subset of genes involved in PTI.These data uncover a dual role for Arabidopsis BOPs in development and defense.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".