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Record W2973383856 · doi:10.1016/j.ibror.2019.07.1014

Analysis of cell diversity in human and mouse basal ganglia by single-cell RNA sequencing

2019· article· en· W2973383856 on OpenAlexaff
Fengjiao Li, Xiang-Shan Yuan, Weiwei Xian, Qiong Liu, Wensheng Li, Guomin Zhou, Edwin Wang, Linya You

Bibliographic record

VenueIBRO Reports · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSingle-cell and spatial transcriptomics
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsBiologySingle-cell analysisCellRNAGeneticsComputational biologyGene

Abstract

fetched live from OpenAlex

The issues related to the bilingual lexical processing are primarily concerned with the rapid involvement of phonological codes in the process of silent word reading.Here, we investigated bilinguals' neurolinguistic activities during L1 (Korean) and L2 (English) translation as well as language-switching during the same or different sensory type of linguistic stimuli.Subjects performed the translation task consisted of four experimental conditions, KK (Korean-Korean), KE (Korean-English), EE (English-English), and EK (English-Korean).Four words on the screen of visual stimulus and the sound of one word out of four words of auditory stimulus were given simultaneously and the condition was randomly selected in each trial.Subjects were instructed to translate what they see and hear in a brief time and to choose the correct answer as fast as they could.The result from a behavioral experiment showed significant correlations between the reaction time and accuracy in EK and EE.Additionally, the negative correlation was found in each condition accompanying speed-accuracy tradeoffs especially when the type of language was different such as EK and KE.Along with the results from a behavioral study, strong BOLD signals in middle frontal gyrus, precuneus, inferior occipital gyrus, BA 18, BA 9 and BA 39 regions were found in contrasts between conditions in fMRI experiment.We found that the brain took a similar route for translation as well as reading and listening to the word irrespective of the types of language.Our findings indicated when the given linguistic stimulus is less exposed one, especially when the stimulus is a sound, more regions are required to translate it into their familiar language.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.209
Teacher spread0.196 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractno

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