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Record W2973641376 · doi:10.1038/s41467-019-12095-8

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

2019· erratum· en· W2973641376 on OpenAlexaff
Xia Jiang, Hilary K. Finucane, Fredrick R. Schumacher, Stephanie L. Schmit, Jonathan P. Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline Kuchenbaecker, Joe Dennis, David V. Conti, Graham Casey, Mia M. Gaudet, Jeroen R. Huyghe, Demetrius Albanes, Melinda C. Aldrich, Angeline S. Andrew, Irene L. Andrulis, Hoda Anton‐Culver, Antonis C. Antoniou, Natalia Antonenkova, Susanne M. Arnold, Kristan J. Aronson, Banu Arun, Elisa V. Bandera, Rósa B. Barkardóttir, Daniel R. Barnes, Jyotsna Batra, Matthias W. Beckmann, Javier Benı́tez, Sara Benlloch, Andrew Berchuck, Sonja I. Berndt, Heike Bickeböller, Stephanie A. Bien, Carl Blomqvist, Stefania Boccia, Natalia Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Hiltrud Brauch, Hermann Brenner, James D. Brenton, Mark N. Brook, Joan Brunet, Hans Brunnström, Daniel D. Buchanan, Barbara Burwinkel, Ralf Bützow, Gabriella Cadoni, Trinidad Caldés, Maria A. Caligo, Ian Campbell, Peter T. Campbell, Géraldine Cancel‐Tassin, Lisa Cannon‐Albright, Daniele Campa, Neil E. Caporaso, André Lopes Carvalho, Andrew T. Chan, Jenny Chang‐Claude, Stephen J. Chanock, Chu Chen, David C. Christiani, Kathleen Claes, Frank Claessens, Judith A. Clements, J. Margriet Collée, Marcia Cruz Correa, Fergus J. Couch, Angela Cox, Julie M. Cunningham, Cezary Cybulski, Kamila Czene, Mary B. Daly, Anna DeFazio, Peter Devilee, Orland Dı́ez, Manuela Gago-Domínguez, Jenny Donovan, Thilo Dörk, Eric J. Duell, Alison M. Dunning, Miriam Dwek, Christopher K. Edlund, Digna R. Velez Edwards, Carolina Ellberg, D. Gareth Evans, Peter A. Fasching, Robert L. Ferris, Triantafillos Liloglou, Jane C. Figueiredo, Olivia Fletcher, Renée T. Fortner, Florentia Fostira, Silvia Franceschi, Eitan Friedman, Steven Gallinger, Patricia A. Ganz, Judy E. Garber, José Á. García-Sáenz, Simon A. Gayther, Graham G. Giles, Andrew K. Godwin, Mark S. Goldberg, David E. Goldgar, Ellen L. Goode, Marc T. Goodman, Gary Goodman, Kjell Grankvist, Mark H. Greene, Henrik Grönberg, Jacek Gronwald, Pascal Guénel, Niclas Håkansson, Per Hall, Ute Hamann, Freddie C. Hamdy, Robert J. Hamilton, Jochen Hampe, Aage Haugen, Florian Heitz, Rolando Herrero, Peter Hillemanns, Michael Hoffmeister, Estrid Høgdall, Yun‐Chul Hong, John L. Hopper, Richard S. Houlston, Peter J. Hulick, David J. Hunter, David G. Huntsman, Gregory Idos, Evgeny N. Imyanitov, Sue A. Ingles, Claudine Isaacs, Anna Jakubowska, Paul A. James, Mark A. Jenkins, Mattias Johansson, Mikael Johansson, Esther M. John, Amit D. Joshi, Radka Kaneva, Beth Y. Karlan, Linda E. Kelemen, Tabea Kühl, Kay‐Tee Khaw, Э. К. Хуснутдинова, Adam S. Kibel, Lambertus A. Kiemeney, Jeri Kim, Susanne K. Kjær, Julia A. Knight, Manolis Kogevinas, Zsofia Kote‐Jarai, Stella Koutros, Vessela N. Kristensen, Jolanta Kupryjańczyk, Martin Lacko, Stephan Lam, Diether Lambrechts, Maria Teresa Landi, Philip Lazarus, Nhu D. Le, Eunjung Lee, Flavio Lejbkowicz, Heinz‐Josef Lenz, Goska Leslie, Davor Lessel, Jenny Lester, Douglas A. Levine, Li Li, Christopher I. Li, Annika Lindblom, Noralane M. Lindor, Geoffrey Liu, Fotios Loupakis, Jan Lubiński, Lovise Mæhle, Christiane Maier, Loı̈c Le Marchand, Sara Margolin, Taymaa May, Lesley McGuffog, Alfons Meindl, Pooja Middha, Austin Miller, Roger L. Milne, Robert J. MacInnis, Francesmary Modugno, Marco Montagna, Vı́ctor Moreno, Kirsten B. Moysich, Lorelei A. Mucci, Kenneth Muir, Anna Marie Mulligan, Katherine L. Nathanson, David E. Neal, Susan L. Neuhausen, Heli Nevanlinna, Polly A. Newcomb, Lisa F. Newcomb, Finn Cilius Nielsen, Liene Ņikitina-Zaķe, Børge G. Nordestgaard, Robert L. Nussbaum, Kenneth Offit, Edith Oláh, Ali Amin Al Olama, Olufunmilayo I. Olopade, Andrew F. Olshan, Håkan Olsson, Ana Osório, Hardev Pandha, Jong Y. Park, Nora Pashayan, Michael T. Parsons, Tanja Pejović, Kathryn L. Penney, Wilbert H.M. Peters, Catherine M. Phelan, Amanda I. Phipps, Dijana Plaseska‐Karanfilska, Miranda Pring, Darya Prokofyeva, Paolo Radice, Kāri Stefánsson, Susan J. Ramus, Leon Raskin, Gad Rennert, Hedy S. Rennert, Elizabeth J. van Rensburg, Marjorie J. Riggan, Harvey A. Risch, Angela Risch, Monique J. Roobol, Barry S. Rosenstein, Mary Anne Rossing, Kim De Ruyck, Emmanouil Saloustros, Dale P. Sandler, Elinor J. Sawyer, Matthew B. Schabath, Johanna Schleutker, Marjanka K. Schmidt, Veronica Wendy Setiawan, Hongbing Shen, Erin M. Siegel, Weiva Sieh, Christian F. Singer, Martha L. Slattery, Karina D. Sørensen, Melissa C. Southey, Amanda B. Spurdle, Janet L. Stanford, Victoria L. Stevens, Sebastian Stintzing, Jennifer Stone, Karin Sundfeldt, Rebecca Sutphen, Anthony J. Swerdlow, Eloíza H. Tajara, Catherine M. Tangen, Adonina Tardón, Jack A. Taylor, M. Dawn Teare, Manuel R. Teixeira, Mary Beth Terry, Kathryn L. Terry, Stephen N. Thibodeau, Mads Thomassen, Line Bjørge, Marc Tischkowitz, Amanda E. Toland, Diana Torres, Paul A. Townsend, Ruth C. Travis, Nadine Tung, Shelley S. Tworoger, Cornelia M. Ulrich, Nawaid Usmani, Celine M. Vachon, Els Van Nieuwenhuysen, Ana Vega, Miguel E. Aguado‐Barrera, Qin Wang, Penelope M. Webb, Clarice R. Weinberg, Stephanie J. Weinstein, Mark C. Weissler, Jeffrey N. Weitzel, Catharine West, Emily White, Alice S. Whittemore, H‐Erich Wichmann, Fredrik Wiklund, Robert Winqvist, Alicja Wolk, Penella J. Woll, Michael O. Woods, Anna H. Wu, Xifeng Wu, Drakoulis Yannoukakos, Wei Zheng, Shanbeh Zienolddiny, Argyrios Ziogas, Kristin K. Zorn, Jacqueline M. Lane, Richa Saxena, Duncan C. Thomas, Brenda Diergaarde, James McKay, Ulrike Peters, Li Hsu, Montserrat García‐Closas, Rosalind A. Eeles, Georgia Chenevix‐Trench, Paul Brennan, Christopher A. Haiman, Jacques Simard, Douglas F. Easton, Stephen B. Gruber, Paul D.P. Pharoah, Alkes L. Price, Bogdan Paşaniuc, Christopher I. Amos, Peter Kraft, Sara Lindström

Bibliographic record

VenueNature Communications · 2019
Typeerratum
Languageen
FieldMedicine
TopicRenal cell carcinoma treatment
Canadian institutionsUniversité LavalMemorial University of NewfoundlandUniversity of AlbertaSinai Health SystemUniversity of British ColumbiaMcGill UniversityCanada Research ChairsQueen's UniversityBC Cancer AgencyVancouver General HospitalPrincess Margaret Cancer CentreMount Sinai HospitalLunenfeld-Tanenbaum Research InstituteCentre hospitalier universitaire de QuébecRoyal Victoria HospitalUniversity Health NetworkUniversity of Toronto
FundersMedical Research CouncilNational Institute of Environmental Health SciencesNational Institute for Health and Care ResearchNational Cancer InstituteCancer Research UKNovo Nordisk FondenWorld Health Organization
KeywordsHeritabilityComputational biologyComputer scienceBiologyGenetics

Abstract

fetched live from OpenAlex

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.075
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.070
Threshold uncertainty score0.235

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.075
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0040.003
Science and technology studies0.0030.002
Scholarly communication0.0040.002
Open science0.0040.002
Research integrity0.0060.011
Insufficient payload (model declined to judge)0.0700.030

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.325
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations15
Published2019
Admission routes1
Has abstractyes

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