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Record W2975051965 · doi:10.15252/embj.2018101323

Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression

2019· article· en· W2975051965 on OpenAlexafffund
Julie Lorent, Eric Kusnadi, Vincent van Hoef, Richard J. Rebello, Matthew Leibovitch, Johannes Ristau, Shan Chen, Mitchell G. Lawrence, Krzysztof J. Szkop, Baila Samreen, Preetika Balanathan, Francesca Rapino, Pierre Close, Patricia Bukczynska, Karin Scharmann, Itsuhiro Takizawa, Gail P. Risbridger, Luke A. Selth, Sebastian A. Leidel, Qishan Lin, Ivan Topisirović, Ola Larsson, Luc Furic

Bibliographic record

VenueThe EMBO Journal · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRNA Research and Splicing
Canadian institutionsMcGill University
FundersNational Cancer InstituteNational Health and Medical Research CouncilFonds de Recherche du Québec - SantéCanadian Institutes of Health ResearchNational Institutes of HealthWalloon excellence in life sciences and biotechnologyGovernment of CanadaDeutsche ForschungsgemeinschaftSwedish Foundation for International Cooperation in Research and Higher EducationCancerföreningen i StockholmCancerfondenDepartment of Health and Human Services, State Government of VictoriaKnut och Alice Wallenbergs StiftelseVetenskapsrådet
KeywordsTranslational researchBiomedicineCancerLibrary scienceMedicineOncologyBiologyPathologyInternal medicineBioinformatics

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.152

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.275
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations50
Published2019
Admission routes2
Has abstractno

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