Gender Differences in Psychologic Parameters in Functional Dyspepsia
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Bibliographic record
Abstract
Purpose: Past studies have demonstrated an association between functional dyspepsia (FD) and psychosocial and psychiatric co-morbidities. Little information exists on gender differences in FD. The purpose of this study was to examine whether psychological factors, somatic symptoms, sleep quality, and quality of life in patients with FD could discriminate between men and women. Methods: The Functional Dyspepsia Treatment Trial (FDTT) is a multicenter, international, randomized clinical trial evaluating the effects of antidepressants on FD symptoms in patients. Baseline data, from 147 patients (117 females) enrolled in the trial, were used. Participants met Rome III criteria for FD with negative endoscopy, no history of depression or use of antidepressants, and no major co-morbidities. At baseline, participants completed validated questionnaires related to psychological profiles; Profile of Mood States (POMS), Symptom Checklist -90 R (SCL-90), Hospital Anxiety Depression Scale (HADS), State-Trait Anxiety Inventory (STAI), Somatic Symptom Checklist (SSC), quality of life (SF-36), pain visual analogue scales (VAS) and Pittsburgh Sleep Quality Index (PSQI). Multiple variable logistic regression was used to identify significant independent predictors in women vs. men. Results: Men were slightly older (mean age of 47.5 years [95% CI 41.6-53.4]) than women (mean age of 44.1 [95% CI 44.5-47.3 ]). The SSC score and the SCL-90 Global Severity Index (GSI) were the most significant predictors, while anxiety, mood states, sleep quality, or quality of life did not have significant independent predictive value (Table).Table: No Caption available.Conclusion: Women reported higher SSC scores. Other psychological factors, quality of life and sleep did not discriminate between genders. Why the GSI score in men is higher than women when the SSC score is known needs further study.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it