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Cardiorespiratory Responses between One-legged and Two-legged Cycling in Patients with Idiopathic Pulmonary Fibrosis

2019· letter· en· W2979817506 on OpenAlexaff
Thomas E. Dolmage, Tom Reilly, Neil Greening, Sally Majd, Bhavesh Popat, Sanjay Agarwal, Felix Woodhead, Rachael A Evans

Bibliographic record

VenueAnnals of the American Thoracic Society · 2019
Typeletter
Languageen
FieldMedicine
TopicChronic Obstructive Pulmonary Disease (COPD) Research
Canadian institutionsWest Park Healthcare Centre
FundersNational Institute for Health and Care Research
KeywordsCardiorespiratory fitnessMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Physical therapyGerontologyFamily medicineInternal medicineDisease

Abstract

fetched live from OpenAlex

International guidelines recommend exercise training within pulmonary rehabilitation (PR)\nfor adults with idiopathic pulmonary fibrosis (IPF) [1]. However, the magnitude of benefits of\nPR in IPF may be less than in COPD [2] and are not sustained [3]. Partitioned muscle training\nhas been investigated for other chronic diseases where a central limitation to exercise\ndominates [4-6]. One-legged cycling partitions the targeted exercising muscle thereby\nreducing the total ventilatory burden for the same muscle specific power. In ventilatory\nlimited patients with COPD, partitioned training increases cardiorespiratory fitness [4, 7]\nmeasured by peak oxygen uptake (V̇\nO2pk) greater than that achieved with conventional twolegged cycle training.\nWe hypothesised that patients with IPF would increase their tolerable exercise time of a leg\nexercising alone (one-legged cycling) compared to two-legged cycling so that the total work\nwould be doubled (the primary outcome). We also aimed to quantify peripheral muscle\naerobic capacity relative to the central capacity by determining the ratio of V̇\nO2pk achieved\nduring one- versus two-legged cycling.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.362
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2019
Admission routes1
Has abstractyes

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Same venueAnnals of the American Thoracic SocietySame topicChronic Obstructive Pulmonary Disease (COPD) ResearchFrench-language works237,207