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Record W2979951654 · doi:10.1042/bio04101022

Age-associated inflammation alters the aging trajectory

2019· article· en· W2979951654 on OpenAlex
Grace Teskey, Cedoljub Bundalovic-Torma, Dawn M. E. Bowdish

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueThe Biochemist · 2019
Typearticle
Languageen
FieldNeuroscience
TopicTryptophan and brain disorders
Canadian institutionsMcMaster University
Fundersnot available
KeywordsWonderFeelingAmbivalenceDiversity (politics)PsychologyGerontologySuccessful agingAppealSocial psychologyMedicineSociologyPolitical science

Abstract

fetched live from OpenAlex

Jonathan Swift said, ‘Every man desires to live long, but no man wishes to be old’. Most of us have ambivalent feelings about aging. We may want a long life, but those extra years hold less appeal if we are too ill to enjoy them. At one extreme of the aging trajectory are those who become frail, immobile and dependent in their 5th or 6th decade. At the other extreme are those who live to 100 or beyond remaining cognitively intact, active and engaged in their communities. We wonder what causes underlie this diversity in the aging process? Why do some of us age well and others poorly? The immune system plays a central role in health in our later years.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.244

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.234
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it