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Record W2980324489

Development of Standard Operating Procedures (SOPs) for the Use of the Model Plant Arabidopsis thaliana in Molecular Biology Research

2019· article· en· W2980324489 on OpenAlexaff
Alex Tetrault, Dana Guhle

Bibliographic record

VenueStudent Research Proceedings · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant tissue culture and regeneration
Canadian institutionsMacEwan University
Fundersnot available
KeywordsArabidopsisArabidopsis thalianaComputational biologyBiologyPlasmidBiotechnologyCloning (programming)GenomeComputer scienceGeneticsDNAGene
DOInot available

Abstract

fetched live from OpenAlex

Arabidopsis thaliana is a model plant used to study molecular processes that control plant growth and development. It is popularly studied due to its easy maintenance, short generation time, fully sequenced genome and high offspring yield. However, plants can be sensitive to environmental changes and require proper handling. Therefore, standard operating procedures (SOPs) for maintaining Arabidopsis must be optimised for the location that they are being maintained. This project was conducted to develop custom SOPs for MacEwan University for future undergraduate molecular biology research with Arabidopsis thaliana. The SOPs define optimal plant growing conditions and provide step-by-step instruction for seed harvest and storage. In addition, techniques necessary for genetic engineering of Arabidopsis were also tested. SOPs regarding plasmid DNA cloning, purification, quantification and remodelling using Escherichia coli were created. Seeds were also harvested and sterilized throughout the course of the study, providing MacEwan University with a dedicated Arabidopsis seed bank. Researchers at MacEwan University interested in using Arabidopsis thaliana now have immediate access to viable seeds and the information necessary for ensuring plant health and proper plasmid DNA preparation.   Faculty Mentor: Melissa Hills Department: Biological Science

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.020
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.022
Threshold uncertainty score0.073

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.020
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0030.002
Science and technology studies0.0020.001
Scholarly communication0.0020.002
Open science0.0030.002
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0220.027

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.163
GPT teacher head0.426
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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Same venueStudent Research ProceedingsSame topicPlant tissue culture and regenerationFrench-language works237,207