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Record W2980324489

Development of Standard Operating Procedures (SOPs) for the Use of the Model Plant Arabidopsis thaliana in Molecular Biology Research

2019· article· en· W2980324489 on OpenAlexaff
Alex Tetrault, Dana Guhle

Bibliographic record

VenueStudent Research Proceedings · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant tissue culture and regeneration
Canadian institutionsMacEwan University
Fundersnot available
KeywordsArabidopsisArabidopsis thalianaComputational biologyBiologyPlasmidBiotechnologyCloning (programming)GenomeComputer scienceGeneticsDNAGene
DOInot available

Abstract

fetched live from OpenAlex

Arabidopsis thaliana is a model plant used to study molecular processes that control plant growth and development. It is popularly studied due to its easy maintenance, short generation time, fully sequenced genome and high offspring yield. However, plants can be sensitive to environmental changes and require proper handling. Therefore, standard operating procedures (SOPs) for maintaining Arabidopsis must be optimised for the location that they are being maintained. This project was conducted to develop custom SOPs for MacEwan University for future undergraduate molecular biology research with Arabidopsis thaliana. The SOPs define optimal plant growing conditions and provide step-by-step instruction for seed harvest and storage. In addition, techniques necessary for genetic engineering of Arabidopsis were also tested. SOPs regarding plasmid DNA cloning, purification, quantification and remodelling using Escherichia coli were created. Seeds were also harvested and sterilized throughout the course of the study, providing MacEwan University with a dedicated Arabidopsis seed bank. Researchers at MacEwan University interested in using Arabidopsis thaliana now have immediate access to viable seeds and the information necessary for ensuring plant health and proper plasmid DNA preparation.   Faculty Mentor: Melissa Hills Department: Biological Science

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.237

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.163
GPT teacher head0.426
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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