Bibliographic record
Abstract
ぶどう膜炎に対する生物学的製剤の使用が本格的に始まったのは，2007年にベーチェット病の難治性網膜ぶどう膜炎に対してインフリキシマブが保険適用となってからである。優れた有効性を有し，ベーチェット病の視力予後を大きく改善させた。2016年9月には非感染性ぶどう膜炎にアダリムマブが保険適用となり，TNF阻害薬はぶどう膜炎治療において重要な位置を占めるに至っている。使用にあたっては感染性ぶどう膜炎との鑑別を行い，適応を見極めることが非常に重要となり，使用中には重篤な感染症などの有害事象に対して十分な注意と適切な対処が必要となる。本稿ではTNF阻害薬使用に伴う感染症の管理について述べる。
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.072 | 0.013 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".