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Record W2981203448 · doi:10.34297/ajbsr.2019.05.000883

The Future of Diagnostic Laboratory Testing in Healthcare

2019· article· en· W2981203448 on OpenAlex
Jawahar Kalra

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAmerican Journal of Biomedical Science & Research · 2019
Typearticle
Languageen
FieldMedicine
TopicClinical Laboratory Practices and Quality Control
Canadian institutionsUniversity of SaskatchewanRoyal University HospitalSaskatchewan Health Authority
Fundersnot available
KeywordsOverdiagnosisHealth careDeliberationRisk analysis (engineering)Test (biology)Diagnostic testConstructiveMedicineComputer science

Abstract

fetched live from OpenAlex

The role of diagnostic laboratory testing in healthcare is evolving. The challenge facing the new era of medicine is the appropriate implementation of new tools and technologies to improve patient care in a cost-effective and sustainable manner. Unprecedented expectations to detect disease earlier and effectively treat all aspects of health and wellbeing create demands for testing which may be premature. Test ordering patterns among physicians are subject to psychological factors such as a desire for certainty and risk aversion, as well as fears of patient dissatisfaction, and litigation. The path towards optimizing the utilization of diagnostic laboratory tests must include strategies to minimize non-contributory testing. Appropriate application and sound clinical reasoning are essential to mitigating overdiagnosis, exponential costs on the healthcare system and unnecessary suffering on the part of the patient. Reducing non-contributory laboratory testing practices would allow for the reallocation of resources toward the protection of imperative practices and the advancement of strategies in preventative and individualized medicine. With thoughtful deliberation and constructive conversations among all stakeholders these challenges, pressures and disruptions have the potential to create innovative strategies to optimize the use of diagnostic laboratory testing in healthcare.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.023
metaresearch head score (Gemma)0.032
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.731
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0230.032
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.006
Science and technology studies0.0000.004
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.476
Teacher spread0.414 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it