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Record W2984990911 · doi:10.7554/elife.04316.009

Author response: Knockdown of hypothalamic RFRP3 prevents chronic stress-induced infertility and embryo resorption

2014· peer-review· en· W2984990911 on OpenAlexaff
Anna C. Geraghty, Sandra E. Muroy, Sheng Zhao, George E. Bentley, Lance J. Kriegsfeld, Daniela Kaufer

Bibliographic record

Venuenot available
Typepeer-review
Languageen
FieldPsychology
TopicNeuroendocrine regulation and behavior
Canadian institutionsCanadian Institute for Advanced Research
Fundersnot available
KeywordsInfertilityFertilityPregnancyMatingChronic stressPhysiologyMedicineReproductive successStressorGene knockdownAndrologyBioinformaticsBiologyInternal medicineGeneticsPsychiatryPopulationApoptosisEnvironmental health

Abstract

fetched live from OpenAlex

A chronic stressor prior to mating has lasting negative consequences on the fertility and fecundity of female rats, which can be prevented by blocking a single hypothalamic reproductive inhibitory hormone.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.069
Threshold uncertainty score0.231

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0690.017

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.072
GPT teacher head0.403
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2014
Admission routes1
Has abstractyes

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