MétaCan
Menu
Back to cohort
Record W2986303780 · doi:10.1038/s41598-019-52608-5

Novel Gd3+-doped silica-based optical fiber material for dosimetry in proton therapy

2019· article· en· W2986303780 on OpenAlexafffund
Cornelia Hoehr, Adriana Morana, Olivier Duhamel, Bruno Capoen, M. Trinczek, Philippe Paillet, Cheryl Duzenli, Mohamed Bouazaoui, Géraud Bouwmans, Andy Cassez, Y. Ouerdane, A. Boukenter, Hicham El Hamzaoui, S. Girard

Bibliographic record

VenueScientific Reports · 2019
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsUniversity of British ColumbiaTRIUMF
FundersEuropean Regional Development FundMinistère de l'Education Nationale, de l'Enseignement Superieur et de la RechercheAgence Nationale de la RechercheEquipexConseil Régional Hauts-de-FranceTRIUMF
KeywordsDopingDosimetryProton therapyOptical fiberFiberMaterials scienceProtonMedicineComputer scienceNuclear medicineOptoelectronicsComposite materialRadiologyRadiation therapyTelecommunicationsPhysics

Abstract

fetched live from OpenAlex

Optical fibers hold promise for accurate dosimetry in small field proton therapy due to their superior spatial resolution and the lack of significant Cerenkov contamination in proton beams. One known drawback for most scintillation detectors is signal quenching in areas of high linear energy transfer, as is the case in the Bragg peak region of a proton beam. In this study, we investigated the potential of innovative optical fiber bulk materials using the sol-gel technique for dosimetry in proton therapy. This type of glass is made of amorphous silica (SiO[Formula: see text]) and is doped with Gd[Formula: see text] ions and possesses very interesting light emission properties with a luminescence band around 314 nm when exposed to protons. The fibers were manufactured at the University of Lille and tested at the TRIUMF Proton Therapy facility with 8.2-62.9 MeV protons and 2-6 nA of extracted beam current. Dose-rate dependence and quenching were measured and compared to other silica-based fibers also made by sol-gel techniques and doped with Ce[Formula: see text] and Cu[Formula: see text]. The three fibers present strong luminescence in the UV (Gd) or visible (Cu,Ce) under irradiation, with the emission intensities related directly to the proton flux. In addition, the 0.5 mm diameter Gd[Formula: see text]-doped fiber shows superior resolution of the Bragg peak, indicating significantly reduced quenching in comparison to the Ce[Formula: see text] and Cu[Formula: see text] fibers with a Birks' constant, k[Formula: see text], of (0.0162 [Formula: see text] 0.0003) cm/MeV in comparison to (0.0333 [Formula: see text] 0.0006) cm/MeV and (0.0352 [Formula: see text] 0.0003) cm/MeV, respectively. To our knowledge, this is the first report of such an interesting k[Formula: see text] for a silica-based optical fiber material, showing clearly that this fiber presents lower quenching than common plastic scintillators. This result demonstrates the high potential of this inorganic fiber material for proton therapy dosimetry.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.285
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations38
Published2019
Admission routes2
Has abstractyes

Explore more

Same venueScientific ReportsSame topicAdvanced Radiotherapy TechniquesFrench-language works237,207