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Record W2986941320

Investigating the Genetic Basis of Antibody Response to Common Infectious Diseases in Commercial Sows

2019· article· en· W2986941320 on OpenAlexaff
Jack C. M. Dekkers, Nick V. L. Serão, John C. S. Harding, Graham Plastow, Leticia P. Sanglard, Benny E Mote, Philip Willson

Bibliographic record

VenueIowa State University animal industry report · 2019
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Virus Infections Studies
Canadian institutionsUniversity of AlbertaUniversity of Saskatchewan
Fundersnot available
KeywordsBiologySelection (genetic algorithm)Robustness (evolution)Antibody responseDiseaseBiotechnologyPlant disease resistanceGeneticsAntibodyGeneMedicineComputer science
DOInot available

Abstract

fetched live from OpenAlex

Disease resistance is one of the most economically important traits affecting pork production. Genetic selection for disease resistance is challenging for the industry since disease traits are not expected to be expressed in the clean genetic nucleus, where selection is performed. Data collected after animals enter commercial farms could be used to estimate breeding values for sires of commercial sows, enabling the selection of robust sires. In this work, we showed that there is genetic variance for antibody response to common infectious diseases in pigs, and major genomic regions were identified for some of these diseases. These results support the possibility of using antibody response to select for robustness in pigs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.062
Threshold uncertainty score0.728

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.257
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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