MétaCan
Menu
Back to cohort

Predicting Long-Term Sustained Disability Progression in Multiple Sclerosis (2002)

2020· article· en· W2987648167 on OpenAlexaff
Sifat Sharmin, Francesca Bovis, Charles B. Malpas, Dana Horáková, Eva Havrdová, Guillermo Izquierdo Ayuso, Sara Eichau, María Trojano, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, François Grand’Maison, Pierre Grammond, Patrizia Sola, Diana Ferraro, Murat Terzi, Raymond Hupperts, Raed Alroughani, Cavit Boz, Vijay Shaygannejad, Vincent Van Pesch, Ludwig Kappos, Jeannette Lechner‐Scott, Roberto Bergamaschi, Recai Türkoğlu, Claudio Solaro, Cristina Ramo‐Tello, Gerardo Iuliano, Franco Granella, Bart Van Wijmeersch, Daniele Litterio A. Spitaleri, R. Fernandez Bolanos, Mark Slee, Pamela McCombe, Julie Prévost, Radek Ampapa, Serkan Özakbaş, José Luis Sánchez-Menoyo, Aysun Soysal, Ostoja Vucic, Thor Petersen, Freek Verheul, Ernest Butler, Suzanne Hodgkinson, Youssef Sidhom, Riadh Gouider, Edgardo Cristiano, Francisco Javier Olascoaga Urtaza, María Laura Saladino, Michael Barnett, Norma Deri, Fraser Moore, Csilla Rózsa, Bassem Yamout, Olga Skibina, Orla Gray, Jamie I. D. Campbell, Ángel Pérez Sempere, Bhim Singhal, Yára Dadalti Fragoso, Cameron Shaw, Allan G. Kermode, Tatjana Petkovska‐Boskova, Bruce Taylor, Magdolna Simó, Norbert Vella, Neil Shuey, Jabir Alkhaboori, Talal Al‐Harbi, Richard Macdonell, José Andrés Domínguez, Ilya Kister, Tünde Csépány, Cárlos Vrech, Krisztina Kovács, Carmen Adella Sîrbu, Stella Hughes, Maria Pia Sormani, Helmut Butzkueven, Tomáš Kalinčík

Bibliographic record

VenueNeurology · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomic variations and chromosomal abnormalities
Canadian institutionsCentre Intégré de Santé et de Services Sociaux des LaurentidesJewish General HospitalCégep de LévisHôpital Notre-Dame
Fundersnot available
KeywordsCzechHumanitiesMedicineCartographyArtGeographyPhilosophy

Abstract

fetched live from OpenAlex

Using global MSBase registry, this study establishes 6-month confirmed disability progression events as indicators of long-term disability worsening suitable for use in randomized clinical trials in multiple sclerosis (MS).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.235
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueNeurologySame topicGenomic variations and chromosomal abnormalitiesFrench-language works237,207