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Record W2987864622 · doi:10.1016/j.ebiom.2019.10.042

To accompany Banas et al., Time for a Paradigm Shift

2019· letter· ca· W2987864622 on OpenAlexaff
Atul Sharma, Tom Blydt‐Hansen

Bibliographic record

VenueEBioMedicine · 2019
Typeletter
Languageca
FieldMedicine
TopicRenal Transplantation Outcomes and Treatments
Canadian institutionsUniversity of British ColumbiaUniversity of Manitoba
Fundersnot available
KeywordsParadigm shiftComputer scienceMedicineComputational biologyBiologyPhilosophyEpistemology

Abstract

fetched live from OpenAlex

The first successful human kidney transplant was performed in 1954, between identical twins without immunosuppression. By the early 1960s, non-identical donors saw reports of acute inflammatory allograft rejection, treatment with corticosteroids, and percutaneous allograft biopsies [1,2]. Despite steady advances in surgical technique, tissue matching, and anti-rejection therapies, the fundamental paradigm did not change much in the subsequent 60 years. Even today, acute rejection (AR) episodes and smoldering subclinical rejection remain the principle determinants of long-term graft survival [3,4], and renal biopsy—despite well-documented risks and costs—remains the diagnostic gold-standard [5] in the face of typically non-specific clinical findings e.g.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.073
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.064
Threshold uncertainty score0.215

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.073
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0030.002
Scholarly communication0.0070.007
Open science0.0030.005
Research integrity0.0110.016
Insufficient payload (model declined to judge)0.0640.040

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.330
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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