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Record W2987965025 · doi:10.1136/ebnurs-2019-103225

What are sensitivity and specificity?

2019· article· en· W2987965025 on OpenAlexaff
Amelia Swift, Roberta Heale, Alison Twycross

Bibliographic record

VenueEvidence-Based Nursing · 2019
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsLaurentian University
Fundersnot available
KeywordsGold standard (test)Test (biology)DiseaseSensitivity (control systems)Measure (data warehouse)AbnormalityMedicineStatisticsComputer scienceInternal medicineMathematicsData miningBiologyPsychiatry

Abstract

fetched live from OpenAlex

Whenever we create a test to screen for a disease, to detect an abnormality or to measure a physiological parameter such as blood pressure (BP), we must determine how valid that test is—does it measure what it sets out to measure accurately? There are lots of factors that combine to describe how valid a test is: sensitivity and specificity are two such factors. We often think of sensitivity and specificity as being ways to indicate the accuracy of the test or measure. In the clinical setting, screening is used to decide which patients are more likely to have a condition. There is often a ‘gold-standard’ screening test—one that is considered the best to use because it is the most accurate. The gold standard test, when compared with other options, is most likely to correctly identify people with the disease (it is specific), and correctly identify those who do not have the disease (it is sensitive). When a test has a sensitivity of 0.8 or 80% it can correctly identify 80% of people who have the disease, but it misses 20%. This smaller group of people have the disease, but the test failed to detect them—this is known as a false negative. A test that has an 80% specificity can correctly identify 80% of people in a group that do not have a disease, but it will misidentify 20% of people. That group of 20% will be identified as having the disease when they do not, this is known as a false positive. See box 1 for definitions of common terms used when describing sensitivity and specificity. Box 1 ### Common terms Sensitivity: the ability of a test to correctly identify patients with a disease. Specificity: the ability of a test to correctly identify people without the disease. True positive: the person has the disease and …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.093
metaresearch head score (Gemma)0.381
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.907
Threshold uncertainty score0.490

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0930.381
Meta-epidemiology (narrow)0.0030.003
Meta-epidemiology (broad)0.0100.006
Bibliometrics0.0140.010
Science and technology studies0.0020.010
Scholarly communication0.0140.022
Open science0.0060.004
Research integrity0.0110.010
Insufficient payload (model declined to judge)0.0180.014

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.669
GPT teacher head0.501
Teacher spread0.168 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations120
Published2019
Admission routes1
Has abstractyes

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