174 Intraoperative Radiotherapy Outcomes in Early Breast Cancer
Bibliographic record
Abstract
Results: Mean age was 69.7.Median follow-up was 35.5 months (range 0-85months).Nineteen of 26 patients had Squamous Cell Carcinoma (SCC), five of 26 (19%) Adenocarcinoma, one of 26 (4%) Clear Cell Carcinoma and one of 26 (4%) Melanoma.Thirteen percent, 71%, 8%, and 8% of patients had FIGO Stages I, II, III, and IV.Local control of 83% and 83%, mDFS of 91 % and 91%, and OS of 80% and 66 %, were respectively achieved at 3 and five years.When limited to SCC only, local control of 88% and 88%, mDFS of 94 % and 94%, and OS of 87% and 70%, were respectively achieved at three and five years.There were no late G3-4 GU/GI toxicity.Acute and late G3 vaginal toxicity occured in 19% and 42% of patients, respectively.Three cases of vaginal necrosis and one suspicion of fistula were reported, all associated with a local progression of the disease.No patient needed Hyperbaric Oxygen Therapy (HBOT).Conclusions: Excellent local control can be achieved with the use of TRUS-guided vaginal brachytherapy in primary vaginal cancer, especially for squamous cell carcinoma, with a favorable toxicity profile.GU and GI toxicities are mild but there is a significant number of G3 vaginal stenosis in this cohort of older patients.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".