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Abstracts

2008· article· en· W2988973088 on OpenAlexaff
Masayuki Amagai, Toshifumi Kobayashi, Akira Shimizu, Koji Nishifuji, Toshiroh Iwasaki, Manabu Ohyama, J. D. REILLY, Hazel Henderson, Paul E. Bowden, Giordana Zanna, Mar Bardagí, María José Docampo, Dolors Fondevila, Anna Bassols, Lluís Ferrer, Joseph M. Blondeau

Bibliographic record

VenueVeterinary Dermatology · 2008
Typearticle
Languageen
FieldVeterinary
TopicInfectious Diseases and Mycology
Canadian institutionsRoyal University HospitalUniversity of Saskatchewan
FundersPfizerAllerganAstraZenecaEli Lilly and CompanyBristol-Myers Squibb
KeywordsCitationLibrary scienceMedicineComputer science

Abstract

fetched live from OpenAlex

Desmosomes are intercellular adhesive junctions of epithelial cells that contain two major transmembrane components, desmogleins (Dsg) and desmocollins (Dsc), which are anchored to intermediate filaments of keratin through interactions with plakoglobin and desmoplakin. Desmosomes play an important role in maintaining the proper structure and barrier function of the epidermis. Dsg and Dsc are both cadherin-type cell-cell adhesion molecules found in desmosomes. Dsg has four isoforms: Dsg1-Dsg4. Dsg1 and Dsg3 are the two major Dsg isoforms in the skin and mucous membranes. In the skin, Dsg1 is expressed throughout the epidermis, but more intensely in the superficial layers, while Dsg3 is expressed in the lower portion of the epidermis, primarily in the basal and parabasal layers. Dsg1 and Dsg3 compensate for each other to hold cells together, when the cells

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.130
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.320
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2008
Admission routes1
Has abstractyes

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