MétaCan
← all works

At-line monitoring of salification process of the antiretroviral lamivudine-saccharinate salt using FT-MIR spectroscopy with multivariate curve resolution

2019· article· en· 10 citations· W2988991979 on OpenAlex· 10.1016/j.vibspec.2019.102992

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: fund_new · design weight: 1678.90 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Analytical chemistry study monitoring a salification process by FT-MIR spectroscopy; the object is a chemical process.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

The study monitors a pharmaceutical salification process using spectroscopy.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: medium

Pharmaceutical process analytical chemistry of lamivudine salt formation.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Vibrational Spectroscopy
Topic
Analytical Chemistry and Chromatography
Field
Chemistry
Canadian institutions
Funders
Fuel Cell Technologies ProgramEuropean Regional Development FundMountain Equipment Co-operative
Keywords
Process analytical technologyDifferential scanning calorimetryChemistryActive ingredientLamivudineMaterials scienceAnalytical Chemistry (journal)Chemical engineeringChromatographyBioinformatics
Has abstract in OpenAlex
no