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Record W2989014249 · doi:10.1016/j.jogc.2019.08.004

Surgical Outcomes in Patients With Endometriosis: A Systematic Review

2019· review· en· W2989014249 on OpenAlexaffvenue
Sukhbir S. Singh, Kerstin Gude, Elizabeth R Perdeaux, William Gattrell, Christian M. Becker

Bibliographic record

VenueJournal of Obstetrics and Gynaecology Canada · 2019
Typereview
Languageen
FieldMedicine
TopicEndometriosis Research and Treatment
Canadian institutionsOttawa HospitalUniversity of Ottawa
FundersAllerganIpsenBayer
KeywordsMedicineEndometriosisPelvic painSurgeryAdverse effectInternal medicine

Abstract

fetched live from OpenAlex

Objective: Among women treated surgically for endometriosisassociated pain, comprehensive data are lacking on the proportions of patients who experience little or no symptom relief, develop recurrent symptoms, or require further surgical treatment for endometriosis.The aim of this study was to assess the efficacy of surgical procedures used to treat endometriosis-associated pain.Methods: Medline and Embase were searched on October 13, 2016.Articles referring to women undergoing surgery for the treatment of endometriosis-associated pain were screened by two independent investigators.For each included treatment arm, data were extracted for the proportion of patients reporting partial or no improvement after surgery for endometriosis-associated pain, pain recurrence, or requirement for further surgery.Results: A total of 38 studies were included.Most studies did not report relevant outcomes to evaluate pain (71.1%) and recurrent surgery (68.4%).Of the women who underwent lesion excision, 11.8% reported no improvement in pain, and 22.6% underwent further surgery.Postoperative pain, recurrent pain, and adverse events were reported by 34.3%, 28.7%, and 14.8%, respectively, of patients who underwent excision or ablation of endometriosis combined with pelvic denervation and in 25.0%, 15.8%, and 8.1% of women who underwent lesion excision alone.Of the patients who were treated surgically for deep endometriosis affecting the bowel and/or bladder, 7.0% experienced recurrent symptoms, and 4.1% underwent further surgery.Conclusion: This review supports the findings of previous studies and highlights the need for standardized reporting and more detailed follow-up after surgery for endometriosis-associated pain. RésuméObjectif : Pour les femmes ayant reçu un traitement chirurgical des douleurs li ees a l'endom etriose, on observe un manque de donn ees sur la proportion de patientes qui eprouvent un soulagement partiel ou inexistant de leurs symptômes, qui connaissent une r ecidive des symptômes ou qui n ecessitent des traitements chirurgicaux suppl ementaires.Cette etude visait a evaluer l'efficacit e des interventions chirurgicales utilis ees pour traiter les douleurs li ees a l'endom etriose.Méthodologie : Des recherches ont et e men ees dans Medline et Embase le 13 octobre 2016.Deux chercheurs ind ependants ont evalu e des articles faisant r ef erence aux femmes qui subissent une intervention chirurgicale pour traiter les douleurs li ees a l'endom etriose.Pour chaque volet de traitement retenu, les donn ees ont et e extraites pour la portion de patientes qui rapportaient une am elioration partielle ou inexistante apr es une intervention chirurgicale pour traiter les douleurs li ees a l'endom etriose, pr esentaient une r ecidive des douleurs ou n ecessitaient une intervention chirurgicale suppl ementaire.Résultats : Un total de 38 etudes ont et e retenues.La plupart des etudes ne rapportaient pas de donn ees pertinentes pour evaluer les douleurs (71,1 %) ni les interventions chirurgicales suppl ementaires (68,4 %).Parmi les femmes qui ont subi une excision des l esions, 11,8 % ont rapport e ne ressentir aucune am elioration des douleurs et 22,6 % ont dû subir une intervention chirurgicale suppl ementaire.On a rapport e des

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How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.026
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.015
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.026
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0090.009
Bibliometrics0.0070.009
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.304
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations82
Published2019
Admission routes2
Has abstractno

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