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Assessment of the oxygen status of the brain during the oral cavity sanation in children aged 3–7 years under general anesthesia on an outpatient setting

2019· article· en· W2989727340 on OpenAlexaboutno aff
O. I. Koval

Bibliographic record

VenueCLINICAL DENTISTRY · 2019
Typearticle
Languageen
FieldNeuroscience
TopicAnesthesia and Neurotoxicity Research
Canadian institutionsnot available
Fundersnot available
KeywordsTemperamentMedicineCognitionOutpatient clinicMontreal Cognitive AssessmentAnesthesiaCognitive impairmentPediatricsPsychologyPsychiatryPersonalityInternal medicine

Abstract

fetched live from OpenAlex

Summary. Unfortunately, today, mental and behavioral disorders in children are quite common. It is proved that one of the main causes of cognitive decline is the disease of the small vessels of the brain. In the literature, there are data on the study of the relationship of cognitive impairment due to functional changes on the background of oxygen starvation of the brain.
 The aim of the study – the article presents the rationale for the need to limit the time for oral rehabilitation in an outpatient setting under general anesthesia in order to preserve the cognitive functions of the brain of the child due to its functional changes in violation of the oxygen status of cerebral vessels.
 Materials and Methods. The oral cavity sanation in the conditions of general anesthesia was conducted in 39 children aged 3–7 years on the basis of the Dental Medical Center at the National Medical University named after O. O. Bohomolets. This age group of children according to the classification of temperament (Thomas and Chess, 1997) includes: 11 children with “mild” temperament; 19 children – with «difficult» temperament; 9 children – temperament «long warms up». In order to monitor the oxygen status of the brain, cerebral oximetry was used.
 Results and Discussion. The linear decrease of rSO2 occurs from 43 minutes. To 60 min. rSO2 = (58.6±0.01) %, with a possible minimum value of 60.26 %. Min rSO2 within the normal range = (60.26±0.22) % is between 57 and 58 minutes. Therefore, in order to prevent the occurrence of brain hypoxia, dental rehabilitation of the oral cavity for children aged 3–7 years should be performed within (40±15) min. Respiratory complications (laryngospasm) in 10.25 % of children were noted during the rehabilitation of the oral cavity under general anesthesia. The mean rSO2 for laryngospasm is (68.83±7.39) %, which is 8.63 % relative to the mean rSO2 of the respective age group (rSO2 = (75.33±2.68) %). SO rSO2 of 16 min. 33 minutes each (≤20 min) by 11.42 % (rSO2 = (60.57±5.44) %). The peak of the decline occurred in 20–21 min. (rSO2 = (53.5±2.45 %) and accounted for 28.97 % of the total group value and 11.67 % of rSO2 directly for laryngospasm. In 75 % of children who had complications in the form of laryngospasm during the rehabilitation of the oral cavity under general anesthesia were noted ≤ 2 weeks after complete recovery for acute respiratory diseases (ARD). In order to study the effect of inflammatory processes of the respiratory tract on the possibility of complications in the process of dental rehabilitation in the outpatient setting under general anesthesia, we selected a group of children who had a history of ≥2 weeks but ≤ 4 weeks (group I) and analyzed the results indices of rSO2 with a group of children who had a history of ARD with a history of ≤ 2 weeks (group II) relative to those of rSO2 in the general group of children aged 3–7 years (group III). rSO2 in children of group I – (68.65±7.72) % ↓ rSO2 from 16 min to 32 minutes (≤20 min) is 14.59 % (rSO2 = (58.63±4.55) %). In the group II of children, rSO2 (74.92±6.84) %) coincides with rSO2 (74.84±6.63) %) in group III.
 Conclusions. Dental sanitation of the oral cavity under general anesthesia on an outpatient basis for children aged 3–7 years has a time limit (40±15) min. A contraindication for routine oral sanitation under general anesthesia on an outpatient basis is the presence of acute respiratory infections in the history of ≤ 2 weeks. In acute dental conditions, if there is a history of acute respiratory infections ≤ 2 weeks, ambulance care on an outpatient basis under general anesthesia is possible within 15 minutes. SpO2 values do not correlate with rSO2 indicators. The method of cerebral oximetry makes it possible to early detect changes in the oxygen balance of the brain and support it in time. The method of cerebral oximetry makes it possible to early detect changes in the oxygen balance of the brain and support it in time.

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How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.027
Threshold uncertainty score0.275

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.391
Teacher spread0.341 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Published2019
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