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AssemblyNet: A large ensemble of CNNs for 3D whole brain MRI segmentation

2020· preprint· en· W2989976667 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueNeuroImage · 2020
Typepreprint
Languageen
FieldComputer Science
TopicAdvanced Neural Network Applications
Canadian institutionsnot available
FundersNational Center for Research ResourcesNational Institute of Neurological Disorders and StrokeNational Institute on Drug AbuseNational Institute of Mental HealthUniversity of California, San DiegoCanadian Institutes of Health ResearchPfizerUniversity of California, Los AngelesMedical Research CouncilNational Institute of Biomedical Imaging and BioengineeringJohnson and JohnsonEngineering and Physical Sciences Research CouncilAstraZenecaGenentechU.S. Food and Drug AdministrationAlzheimer's Drug Discovery FoundationNational Institutes of HealthNational Institute on AgingMinisterio de Asuntos Económicos y Transformación Digital, Gobierno de EspañaEisaiStavros Niarchos FoundationChild Mind InstituteNorthern California Institute for Research and EducationCentre National de la Recherche ScientifiqueGE HealthcareAlzheimer's Disease Neuroimaging InitiativeScience and Industry Endowment FundSchering-PloughBayer ScheringMinisterio de Economía y CompetitividadMedpaceAbbott LaboratoriesCommonwealth Scientific and Industrial Research OrganisationNational Health and Medical Research CouncilLeon Levy FoundationF. Hoffmann-La RocheCincinnati Children's Hospital Medical CenterAgence Nationale de la RechercheEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentGlaxoSmithKlineBristol-Myers SquibbNational Institute of Child Health and Human DevelopmentEli Lilly and CompanyAlzheimer's AssociationNvidiaInnogeneticsElanNovartisSynarcInstitut National de la Santé et de la Recherche MédicaleDana FoundationRoche
KeywordsComputer scienceArtificial intelligenceRobustness (evolution)SegmentationConvolutional neural networkPattern recognition (psychology)Machine learningConsistency (knowledge bases)VotingDeep learning

Abstract

fetched live from OpenAlex

Whole brain segmentation of fine-grained structures using deep learning (DL) is a very challenging task since the number of anatomical labels is very high compared to the number of available training images. To address this problem, previous DL methods proposed to use a single convolution neural network (CNN) or few independent CNNs. In this paper, we present a novel ensemble method based on a large number of CNNs processing different overlapping brain areas. Inspired by parliamentary decision-making systems, we propose a framework called AssemblyNet, made of two "assemblies" of U-Nets. Such a parliamentary system is capable of dealing with complex decisions, unseen problem and reaching a relevant consensus. AssemblyNet introduces sharing of knowledge among neighboring U-Nets, an "amendment" procedure made by the second assembly at higher-resolution to refine the decision taken by the first one, and a final decision obtained by majority voting. During our validation, AssemblyNet showed competitive performance compared to state-of-the-art methods such as U-Net, Joint label fusion and SLANT. Moreover, we investigated the scan-rescan consistency and the robustness to disease effects of our method. These experiences demonstrated the reliability of AssemblyNet. Finally, we showed the interest of using semi-supervised learning to improve the performance of our method.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.717
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.319
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it