Development of the human placenta
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.
Abstract
development in mammals. In humans, defective placental formation underpins common pregnancy disorders such as pre-eclampsia and fetal growth restriction. The great variation in placental types across mammals means that animal models have been of limited use in understanding human placental development. However, new tools for studying human placental development, including 3D organoids, stem cell culture systems and single cell RNA sequencing, have brought new insights into this field. Here, we review the morphological, molecular and functional aspects of human placental formation, with a focus on the defining cell of the placenta - the trophoblast.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Development
- Topic
- Pregnancy and preeclampsia studies
- Field
- Medicine
- Canadian institutions
- —
- Funders
- Medical Research CouncilRoyal SocietyMedical Research Council CanadaWellcome Trust
- Keywords
- BiologyPlacentaTrophoblastPlacentationIntrauterine growth restrictionCytotrophoblastPlacenta DiseasesCell biologyFetusPregnancyGenetics
- Has abstract in OpenAlex
- yes