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Record W2990870090 · doi:10.1289/isee.2011.01198

AGRICOH, A NEWYLY FORMED CONSORTIUM OF AGRICULTURAL COHORTS

2011· article· en· W2990870090 on OpenAlexaffabout
Maria E. Leon, Laura E. Beane Freeman, Jeroen Douwes, Jane A. Hoppin, Hans Kromhout, Pierre Lebailly, Karl-Christian Nordby, Marc B. Schenker, Joachim Schüz, Stephen C. Waring, Michael C.R. Alavanja, Isabella Annesi‐Maesano, Isabelle Baldi, Mohamed Aqiel Dalvie, Giles Ferro, Béatrice Fervers, Hilde Langseth, Leslie London, Charles F. Lynch, John McLaughlin, James A. Merchant, Punam Pahwa, Torben Sigsgaard, Leslie Stayner, Catharina Wesseling, Keun-Young Yoo, Shelia Hoar Zahm, Kurt Straíf, Aaron Blair

Bibliographic record

VenueISEE Conference Abstracts · 2011
Typearticle
Languageen
FieldEnvironmental Science
TopicHealth, Environment, Cognitive Aging
Canadian institutionsUniversity of SaskatchewanCancer Care Ontario
Fundersnot available
KeywordsAgricultureInternational agencyCohortEnvironmental healthHarmonizationMedicineBiobankCohort studyAgency (philosophy)CancerGeographyPathologyBiologyBioinformaticsSocial science

Abstract

fetched live from OpenAlex

Background and Aims: Chronic exposure to pesticides has endocrine, immunologic and neurologic disrupting properties and other toxic effects believed to be associated with certain cancers, unfavorable reproductive outcomes, neurologic disorders and other health outcomes. Farming and other agricultural jobs are among the occupations with the highest exposures to pesticides. AGRICOH is a consortium of agricultural cohort studies that offers the opportunity to investigate the role of pesticides, and other exposures, in the etiology of several health outcomes. This poster presentation provides a description of AGRICOH to disseminate its formation and future research plans. Methods: Characteristics of the cohorts integrating AGRICOH, data harmonization plans and research concepts to be studied will be illustrated in the poster presentation including the construction of pesticide crop exposure matrices. Results: AGRICOH is a consortium of 22 agricultural cohort studies initiated by the US National Cancer Institute (NCI) and coordinated by the International Agency for Research on Cancer (IARC) since October 2010. The consortium includes cohorts from 9 countries: South Africa (1), Canada (3), Costa Rica (2), USA (6), Korea (1), New Zealand (2), Denmark (1), France (3) and Norway (3). AGRICOH aspires to promote and sustain collaboration and pooling of data to investigate the association between a wide range of agricultural exposures and a wide range of health outcomes, with a particular focus on associations that cannot easily be addressed in individual studies because of rare exposures (e.g. use of infrequently applied pesticides) or relatively rare outcomes (e.g. certain types of cancer, neurologic and auto-immune diseases). Conclusions: AGRICOH represents a great resource for studying cancer, respiratory, neurologic, and auto-immune diseases as well as reproductive and allergic disorders, injuries and overall mortality in association with a wide array of exposures, prominent among these the application of pesticides.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.478
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.240
Teacher spread0.200 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes2
Has abstractyes

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