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Record W2991191815 · doi:10.1111/anae.14892

An international multidisciplinary consensus statement on fasting before procedural sedation in adults and children

2019· review· en· W2991191815 on OpenAlexaff
S. M. Green, Piet Leroy, Mark G. Roback, Michael G. Irwin, Gary Andolfatto, Franz E Babl, Egidio Barbi, Luciane Rezende Costa, Anthony Absalom, Douglas W. Carlson, Baruch Krauss, J Roelofse, V. M. Yuen, Eduardo A Alcaino, Paulo Sucasas Costa, Keira P. Mason

Bibliographic record

VenueAnaesthesia · 2019
Typereview
Languageen
FieldMedicine
TopicEnhanced Recovery After Surgery
Canadian institutionsLions Gate HospitalUniversity of British Columbia
FundersMedical Research CouncilNational Health and Medical Research CouncilFundação de Amparo à Pesquisa do Estado de GoiásCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorConselho Nacional de Desenvolvimento Científico e TecnológicoRoyal Children's Hospital FoundationChildren's Hospital Foundation
KeywordsMedicineSedationChokingLaryngospasmAspiration pneumoniaIntensive care medicineAnesthesiaPneumoniaInternal medicine

Abstract

fetched live from OpenAlex

The multidisciplinary International Committee for the Advancement of Procedural Sedation presents the first fasting and aspiration prevention recommendations specific to procedural sedation, based on an extensive review of the literature. These were developed using Delphi methodology and assessment of the robustness of the available evidence. The literature evidence is clear that fasting, as currently practiced, often substantially exceeds recommended time thresholds and has known adverse consequences, for example, irritability, dehydration and hypoglycaemia. Fasting does not guarantee an empty stomach, and there is no observed association between aspiration and compliance with common fasting guidelines. The probability of clinically important aspiration during procedural sedation is negligible. In the post-1984 literature there are no published reports of aspiration-associated mortality in children, no reports of death in healthy adults (ASA physical status 1 or 2) and just nine reported deaths in adults of ASA physical status 3 or above. Current concerns about aspiration are out of proportion to the actual risk. Given the lower observed frequency of aspiration and mortality than during general anaesthesia, and the theoretical basis for assuming a lesser risk, fasting strategies in procedural sedation can reasonably be less restrictive. We present a consensus-derived algorithm in which each patient is first risk-stratified during their pre-sedation assessment, using evidence-based factors relating to patient characteristics, comorbidities, the nature of the procedure and the nature of the anticipated sedation technique. Graded fasting precautions for liquids and solids are then recommended for elective procedures based upon this categorisation of negligible, mild or moderate aspiration risk. This consensus statement can serve as a resource to practitioners and policymakers who perform and oversee procedural sedation in patients of all ages, worldwide.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.104
metaresearch head score (Gemma)0.122
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.104
Threshold uncertainty score0.549

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1040.122
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.006
Bibliometrics0.0060.003
Science and technology studies0.0030.003
Scholarly communication0.0040.004
Open science0.0060.009
Research integrity0.0090.011
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.342
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations178
Published2019
Admission routes1
Has abstractyes

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