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Visualizing structure and transitions in high-dimensional biological data

2019· article· en· 1,157 citations· W2993894543 on OpenAlex· 10.1038/s41587-019-0336-3

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.012
GPT teacher head0.254
Teacher spread
0.242 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Biotechnology
Topic
Single-cell and spatial transcriptomics
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Université de MontréalUniversité du QuébecMila - Quebec Artificial Intelligence Institute
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute of General Medical SciencesDefense Advanced Research Projects AgencyU.S. Department of Health and Human ServicesNational Institutes of HealthAlfred P. Sloan FoundationNational Human Genome Research InstituteGruber FoundationU.S. Department of Defense
Keywords
VisualizationComputer scienceVariety (cybernetics)EmbeddingNonlinear dimensionality reductionMetric (unit)Manifold (fluid mechanics)Identification (biology)Biological dataComputational biologyData miningBiologyPattern recognition (psychology)Artificial intelligenceBioinformaticsDimensionality reductionEcology
Has abstract in OpenAlex
no