MétaCan
Menu
Back to cohort
Record W2994998364

Особенности взаимодействия in vitro остеобластоподобных клеток MG-63 с поверхностью сплавов системы Ti-ZrNb, обладающих памятью формы

2019· article· ru· W2994998364 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueВестник Московского университета. Серия 16. Биология · 2019
Typearticle
Languageru
FieldMaterials Science
TopicTitanium Alloys Microstructure and Properties
Canadian institutionsÉcole de Technologie Supérieure
Fundersnot available
KeywordsAlloyMicrostructureMaterials scienceOsteoblastParietal boneActin cytoskeletonFibroblastCytoskeletonBiomedical engineeringIn vitroComposite materialChemistryBiologyAnatomyCellBiochemistryMedicine
DOInot available

Abstract

fetched live from OpenAlex

The paper studies the influence of the Ti-Zr-Nb (TZN) shape memory alloys surface on adhesion, proliferation, viability and actin cytoskeleton organization of osteoblast-like cells MG-63. The studied materials have a unique combination of mechanical properties that determine their prospects for creating bone implants with high biomechanical compatibility: low value of the Young’s modulus and superelastic behavior, similar to the behavior of bone tissue. We used thin plates of the experimental alloy TZN and the Ti-Al-Nb medical alloy (TAN) as a control material. A study of the growth dynamics of the MG-63 cell culture was made using the MTT test and counting the number of nuclei per unit area using scanning microscopy. It was found that on 4 and 7 days the number of cells on the TZN alloy is higher than on the TAN alloy. This may be due to the influence of the qualitative and quantitative composition of materials on the surface microstructure and chemistry. The viability over the cultivation time was close to 100% on both alloys. The analysis of cytoskeleton images showed the predominance of fibrillary actin on samples of the TZN system, as well as the organization characteristic of fibroblast-like polygonal cells.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Scholarly communication, Open science, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.310
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.001
Meta-epidemiology (narrow)0.0040.004
Meta-epidemiology (broad)0.0050.002
Bibliometrics0.0020.003
Science and technology studies0.0010.002
Scholarly communication0.0030.005
Open science0.0060.003
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0320.034

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.213
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it