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Record W2995650760 · doi:10.11648/j.ijcm.20190304.13

Pharmacological and Clinical Efficacy of American Ginseng (<i>Panax Quinquefolius</i>): A Mini Review

2019· review· en· W2995650760 on OpenAlexaboutno aff
Vandenhouten Eric E., Li Yan, Ying Wang

Bibliographic record

VenueInternational Journal of Chinese Medicine · 2019
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGinseng Biological Effects and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsGinsengAmerican ginsengTraditional medicineConsumer safetyBiotechnologyMedicineHorticultureBusinessBiologyAlternative medicine

Abstract

fetched live from OpenAlex

American Ginseng (<i>Panax quinquefolius</i>, AG) is a standout amongst the most perceived herbal botanicals in Oriental Medicine and the alternative healthcare market. In spite of the fact that AG is not as broadly studied as <i>Panax Ginseng</i>, none the less, AG is one of the best-selling herbs in the world market, and has gathered expanding attention from researchers as of late. AG is grown in the United States of America, Canada, and The People's Republic of China, on subject of AG industry and quality standards Wisconsin Ginseng is considered to be the gold standard for the highest quality grown worldwide. AG has been farmed in Wisconsin, U.S., for more than 100 years, dating back to the 1800’s which birthed the artificially propagated industry. Today, Wisconsin Ginseng farmers account for 95 percent of the total cultivated AG production of the United States which continues to attract the studies of researcher professionals to the environmentally clean and regulated grown Wisconsin source of origin. Ongoing studies have demonstrated that through the numerous unregulated cultivated procedures that AG is grown, fungal molds, pesticides, and various metals and residues have contaminated the crops. Scientific investigations of AG in the past decade have increased drastically due to the increasing demand of herbal derived biomedicines from natural botanical plant sources that have demonstrated significant potential in clinical efficacy of important diseases. AG Past studies demonstrated have shown ginseng saponins called ginsenosides are the major active constituents in AG. The investigations of AG were relatively limited in the previous decade, but some encouraging advances have been accomplished in understanding the chemistry, pharmacology and structure-function relationship of AG and its clinical efficacy. In this manner, we review pharmacological effects of the ginsenosides, also the clinical efficacy on the cardiovascular system, immune system, and nervous system as well as metabolism and anti-cancer effects. Concentrating on the clinical evidence has indicated particular effectiveness in specific diseases, such as diabetes mellitus, arterial stiffness, neurocognitive disorders, and cancer fatigue as a recommended adjunct treatment along with supplementing conventional therapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.949
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.473
Teacher spread0.394 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2019
Admission routes1
Has abstractyes

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