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Particulate Matter Exposure and Attention-Deficit/Hyperactivity Disorder in Children: A Systematic Review of Epidemiological Studies

2019· review· en· 62 citations· W2995979190 on OpenAlex· 10.3390/ijerph17010067

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

About CanadaIts subject is Canada, wherever its authors sit.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: about_only · design weight: 3321.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Systematic review of epidemiological studies on particulate matter exposure and ADHD; uses synthesis to answer an etiological question.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

It conducts a systematic review to answer a clinical epidemiological question, not to study evidence synthesis.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: high

Epidemiological systematic review of PM exposure and ADHD; clinical/health question.

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is the most common cognitive and behavioural disorder affecting children, with a worldwide-pooled prevalence of around 5%. Exposure to particulate matter (PM) air pollution is suspected to be associated with autism spectrum disorders and recent studies have investigated the relationship between PM exposure and ADHD. In the absence of any synthesis of the relevant literature on this topic, this systematic review of epidemiological studies aimed to investigate the relationship between the exposure of children to PM and ADHD and identify gaps in our current knowledge. In December 2018, we searched the PubMed and EMBASE databases. We only included epidemiological studies carried out on children without any age limit, measuring PM exposure and health outcomes related to ADHD. We assessed the quality of the articles and the risk of bias for each included article using the Newcastle-Ottawa Scale and the Office of Health Assessment and Translation (OHAT) approach, respectively. The keyword search yielded 774 results. Twelve studies with a total number of 181,144 children met our inclusion criteria, of which 10 were prospective cohort studies and 2 were cross-sectional studies. We subsequently classified the selected articles as high or good quality studies. A total of 9 out of the 12 studies reported a positive association between PM exposure to outdoor air pollution and behavioral problems related to attention. Despite these results, we found a significant degree of heterogeneity among the study designs. Furthermore, 11 studies were judged to be at a probably high risk of bias in the exposure assessment. In conclusion, we opine that further high quality studies are still needed in order to clarify the association between PM exposure and ADHD diagnosis.

Stored with the screening record, where it is evidence for the labels above.

The record

Venue
International Journal of Environmental Research and Public Health
Topic
Attention Deficit Hyperactivity Disorder
Field
Medicine
Canadian institutions
Funders
Keywords
EpidemiologyAttention deficit hyperactivity disorderMedicineEnvironmental healthCohort studySystematic reviewEnvironmental epidemiologyPsychiatryPediatricsMEDLINEPathology
Has abstract in OpenAlex
yes