Addition reactions and diazomethane capture by the intramolecular P–O–B FLP: <i>t</i>Bu<sub>2</sub>POBcat
Bibliographic record
Abstract
FLPs, R2POBcat (R = tBu 1, Mes 2), are readily derived from the reactions of the corresponding phosphine oxides, nBuLi and ClBcat. Despite the poor Lewis acidity of boron, these species react with PhOH, CO2, CS2, PhNCO, MesCNO, O2, 9,10-phenanthrenedione, and diazomethanes to effect FLP addition reactions affording a series of heterocycles. The reaction of 1 with EtO2CCHN2 gives the bicyclic product, EtO2CCHN2(tBu2POBcat)2. High-level DFT calculations reveal that these cyclization processes proceed via 1,1-addition to the terminal N of diazomethane followed by 1,2-boron-migration affording the five membered rings. The reaction of the EtO2CCHN2 derivative with the second equivalent of FLP 1 is attributed to less steric demands.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".