Adapted Technological Platform for Screening and Identifying Compounds Capable of In vivo Spinal Network-mediated Reflex Ejaculation in Non-anesthetized, Chronic Paraplegic Mice: Evidence of Clonidine-elicited Seminal Emission
Bibliographic record
Abstract
Several drugs have been shown to facilitate locomotor rhythmogenesis and treadmill training after Spinal Cord Injury (SCI). Clonidine, an alpha-adrenoceptor agonist, is of particular interest given its well-known effects on facilitation of reflex-induced spinal stepping in acute or chronic complete lowthoracic spinal cord-transected (Tx) cats. Since locomotion and ejaculation are controlled by neuronal networks located in the same area of the spinal cord (i.e., upper-to mid-lumbar segments), we hypothesized that clonidine may have comparable effects on reflex ejaculation in
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.021 | 0.015 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".