Acousto optic imaging beyond the acoustic diffraction limit using speckle decorrelation
Why this work is in the frame
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Bibliographic record
Abstract
Abstract Acousto-optic imaging (AOI) enables optical-contrast imaging deep inside scattering samples via localized ultrasound modulation of scattered light. However, the resolution in AOI is inherently limited by the ultrasound focus size, prohibiting microscopic investigations. In recent years advances in the field of digital wavefront-shaping allowed the development of novel approaches for overcoming AOI’s acoustic resolution limit. However, these approaches require thousands of wavefront measurements within the sample speckle decorrelation time, limiting their application to static samples. Here, we show that it is possible to surpass the acoustic resolution-limit with a conventional AOI system by exploiting the natural dynamics of speckle decorrelations rather than trying to overcome them. We achieve this by adapting the principles of super-resolution optical fluctuations imaging (SOFI) to AOI. We show that naturally fluctuating optical speckle grains can serve in AOI as the analogues of blinking fluorophores in SOFI, enabling super-resolution by statistical analysis of fluctuating acousto-optic signals.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it