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Record W2998042392

A Comparative Study Between Apparent Diffusion Imaging and Correlated Diffusion Imaging for Prostate Cancer

2019· article· en· W2998042392 on OpenAlex
Yuchen He, Earvin S. Tio, Linda Wang, Chris Dulhanty, Farzad Khalvati, Masoom A. Haider, Alexander Wong

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Computational Vision and Imaging Systems · 2019
Typearticle
Languageen
FieldMedicine
TopicMRI in cancer diagnosis
Canadian institutionsnot available
Fundersnot available
KeywordsProstate cancerMedicineMagnetic resonance imagingGrading (engineering)Effective diffusion coefficientHistopathologyDiffusion MRICancerCancer detectionRadiologyModality (human–computer interaction)ProstateDiffusion-Weighted Magnetic Resonance ImagingDiffusion imagingNuclear medicinePathologyArtificial intelligenceInternal medicineComputer science
DOInot available

Abstract

fetched live from OpenAlex

Prostate cancer is the second most common cancer in men world-wide, with approximately 174,650 new cases diagnosed in 2019 inthe U.S. [1]. However, prognosis is relatively good given sufficientlyearly detection during the non-metastatic stage, motivating the needfor fast and reliable cancer screening methods. Diffusion weightedimaging is a magnetic resonance imaging technique that is gainingtraction as a noninvasive method for cancer screening. In 2013, anew form of diffusion weighted imaging called correlated diffusionimaging (CDI) was introduced as a potential candidate modality forbuilding computer-aided clinical decision support systems [2]. Weperform a large scale study, across 101 patient cases with full PI-RADS score and histopathology, to compare the performance ofcorrelated diffusion imaging in prostate cancer detection and localization to apparent diffusion coefficient maps, the most commonlyused diffusion weighted imaging-derived imaging modality in can-cer grading. Using threshold-based classification, experimental results showed that CDI achieves higher specificity at high sensitivityvalues of 90% and 95%, suggesting that CDI is well suited for scenarios where high sensitivity is crucial, such as cancer screening.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.352
Threshold uncertainty score0.738

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.348
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it