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Record W2999414835 · doi:10.1101/2020.01.10.901470

Serological evidence of Rift Valley fever infection and risk factors among one-humped camels ( <i>Camelus dromedarius</i> ) in Northern Nigeria

2020· preprint· en· W2999414835 on OpenAlexaff
Andrew M. Adamu, Yila Simon Ayo, Allam Lushakyaa, Sackey Anthony, Alhaji Nma Bida, Garba Bello Sikiti, Mambula-Machunga Salamatu, N Daniel, Idoko Sunday Idoko, E.O. Balogun, Owolodun Olajide Adewale, D. A. Adamu

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2020
Typepreprint
Languageen
FieldMedicine
TopicViral Infections and Vectors
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsRift Valley feverLivestockVeterinary medicineGeographySocioeconomicsSerologyMedicineDemographyEnvironmental healthOutbreakVirologyImmunology

Abstract

fetched live from OpenAlex

Abstract Background Rift Valley fever (RVF) is a zoonotic disease that has become emerging and re-emerging in some regions of the world, infecting livestock and humans. One-humped camels are important economic livestock species in Africa used for traction, transportation, and food. Regional and international trade has continued to increase the risk of this disease, spreading widely and causing severe economic and public health catastrophes in affected regions. In spite of these risks, there is a dearth of information about the status of RVF in camels in Nigeria. This study was carried out to determine the prevalence of the RVF virus in one-humped camels in Nigeria and identify the risk factors associated with the disease. Methods A cross-sectional study with simple random sampling was carried out in seven local government areas of Jigawa and Katsina States. The sera from camels were tested for anti-RVFV IgG. Camel owners were administered a structured questionnaire to ascertain their knowledge, attitude, and practice. Results An overall prevalence of 19.9% (95% CI; 17.07-22.90) was recorded. Based on age groups, the highest prevalence of 20.9% (95% CI; 17.00-25.31) was obtained among older camels (6-10 years), while female camels recorded a high prevalence of 20.4% (95%CI; 15.71-25.80). Sule Tankar-kar recorded the highest prevalence with 33% (95%CI; 1.31-4.72, p= 0.007) and OR 2.47 in Jigawa State while Mai’adua had 24.7% (95%CI; 0.97-2.73, p=0.030) with OR 1.62 in Katsina State respectively. From the risk map, local government areas bordering Niger Republic were at a high risk of RVF. Only high rainfall was not significantly linked with RVF occurrence among nomadic camel pastoralists (95%CI 0.93-5.20; p=0.070). Conclusion There is a need for the country to have quarantine units across borders for screening animals coming from neighbouring countries for transboundary infectious diseases such as RVF. Author Summary Rift Valley fever is a viral haemorrhagic fever that affects animals and humans with high mortality. Recently there has been increased demand in camel meat and products for food and therapeutic purposes. Climate change, coupled with insecurity in the Sahel, has had a significant impact on transhumance activities where camels and their owners move to different countries in search of pasture for their animals. Though Nigeria has not reported an outbreak of Rift Valley fever despite serological evidence in various animal species, there is a need to assess RVF in camels, which is a critical animal species, involved in transhumance with the potential of introducing transboundary diseases into new areas. The study assessed the presence of antibodies in camels, identified risk factors associated with the disease in camels and areas at risk for the disease. Our study found a seroprevalence of 19.9% in camels in two northern states of Nigeria, which shares a boundary with the Niger Republic that recently reported an outbreak. Our findings suggest that areas in proximity to Niger Republic are at a high risk to the disease and camels belonging to transhumance pastoralists are highly likely to contract Rift Valley fever since they are exposed to various ecological and environmental factors that precipitate the disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.255
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations3
Published2020
Admission routes1
Has abstractyes

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