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Record W3002870705

Medical Scope:IBDにおけるマイクロバイオーム最前線

2019· article· ja· W3002870705 on OpenAlexvenueno aff
吉松 裕介, ほか

Bibliographic record

VenuePharma Medica · 2019
Typearticle
Languageja
FieldEngineering
TopicMilitary Technology and Strategies
Canadian institutionsnot available
Fundersnot available
KeywordsScope (computer science)MedicineBusinessComputer science
DOInot available

Abstract

fetched live from OpenAlex

炎症性腸疾患(IBD)は再燃寛解を繰り返す慢性炎症性腸疾患で,原因不明であるが,遺伝的素因・環境因子・腸管免疫が複合的に関与して発症することが想定されている。なかでもその疾患の病態の中心と考えられてきた腸管免疫をターゲットにした免疫統御療法がIBD治療の中核となっている。近年,次世代シークエンサーを用いた解析により,腸内細菌叢が,IBDの複合的要因のいずれとも関連があることが明らかになった。新たな治療ターゲットである腸内細菌叢に着目してさまざまな研究が行われており,いまだIBDの治療法としての確立には至っていないが,今後の検討次第では,特に既存治療抵抗例や不耐例のIBD患者にとって光明となりうるであろう。

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.680
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0690.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.262
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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