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Record W3002870705

Medical Scope:IBDにおけるマイクロバイオーム最前線

2019· article· ja· W3002870705 on OpenAlexvenueno aff
吉松 裕介, ほか

Bibliographic record

VenuePharma Medica · 2019
Typearticle
Languageja
FieldEngineering
TopicMilitary Technology and Strategies
Canadian institutionsnot available
Fundersnot available
KeywordsScope (computer science)MedicineBusinessComputer science
DOInot available

Abstract

fetched live from OpenAlex

炎症性腸疾患(IBD)は再燃寛解を繰り返す慢性炎症性腸疾患で,原因不明であるが,遺伝的素因・環境因子・腸管免疫が複合的に関与して発症することが想定されている。なかでもその疾患の病態の中心と考えられてきた腸管免疫をターゲットにした免疫統御療法がIBD治療の中核となっている。近年,次世代シークエンサーを用いた解析により,腸内細菌叢が,IBDの複合的要因のいずれとも関連があることが明らかになった。新たな治療ターゲットである腸内細菌叢に着目してさまざまな研究が行われており,いまだIBDの治療法としての確立には至っていないが,今後の検討次第では,特に既存治療抵抗例や不耐例のIBD患者にとって光明となりうるであろう。

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.026
Threshold uncertainty score0.086

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0030.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0260.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.262
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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