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3D Visualization of Depression and Anxiety

2020· article· en· W3003884063 on OpenAlexaboutno aff
Marissa Stalets, Emily Rodgers, David Dufeau

Bibliographic record

VenueThe FASEB Journal · 2020
Typearticle
Languageen
FieldMedicine
TopicSpaceflight effects on biology
Canadian institutionsnot available
Fundersnot available
KeywordsAnxietyContext (archaeology)Depression (economics)Psychological interventionMental healthProcess (computing)Plan (archaeology)Action planPsychologyMedicineComputer sciencePsychiatry

Abstract

fetched live from OpenAlex

We present a novel and technologically enhanced teaching tool geared towards both patients, students, and clinicians with the primary goal of educating these groups about the anatomical and biochemical implications of various syndromes involving depression and anxiety. Our secondary goal is to inform patients, students, and clinicians about the most common treatment methods used to treat these syndromes. We achieved this by mapping the mesolimbic system, otherwise known as the “reward pathway,” and other relevant neuroanatomical structures using a high‐resolution cryosection dataset made available by the Big Brain project at McGill University and constructing 3D visualized models using 3D analysis software tools. The results of this project were compiled into a series of three interactive educational modules serving each of our goals. The first module described the neuroanatomical structures involved in syndromes of depression and anxiety along with their functions. The second module describes various forms of clinical depression and treatment options, including the mechanism of action and how it applies to the underlying disease process. The third module did the same but described anxiety rather than depression. This tool is valuable to patients and care providers alike because it explains neuroanatomical and biochemical aspects of these syndromes in a straight‐forward and easy‐to‐understand visual manner. It also describes the context of the best pharmacological interventions for each syndrome, which is a substantial step to help engage patients in their personalized mental health treatment plan. Support or Funding Information Thank you to Dr. David Dufeau and Marian University College of Osteopathic Medicine for the resources and guidance throughout this research project.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.030
Threshold uncertainty score0.099

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.289
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes1
Has abstractyes

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