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Record W3004555358 · doi:10.1101/2020.02.06.937342

The Arabidopsis gene <i>RGO</i> mediates cytokinin responses and increases seed yield

2020· preprint· en· W3004555358 on OpenAlexafffund
Jhadeswar Murmu, Ghislaine Allard, Denise Chabot, Eiji Nambara, Raju Datla, Shelley R. Hepworth, Rajagopal Subramaniam, Jas Singh

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2020
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Molecular Biology Research
Canadian institutionsGlobal Institute for Water SecurityCarleton UniversityUniversity of TorontoPublic Health Agency of CanadaAgriculture and Agri-Food Canada
FundersPrecursory Research for Embryonic Science and TechnologyJapan Science and Technology AgencyAgriculture and Agri-Food Canada
KeywordsArabidopsisSiliqueBiologyCytokininArabidopsis thalianaReporter geneGUS reporter systemGeneEctopic expressionCell biologyGene expressionBotanyGeneticsMutantAuxin

Abstract

fetched live from OpenAlex

Abstract A novel gene, At1g77960 , from Arabidopsis thaliana was characterized. At1g77960 transcripts accumulate to very high levels in plants ectopically overexpressing the Golden2-like1 ( GLK1 ) transcription factor and is designated as a R esponse to G LK1 O verexpression ( RGO ) gene. RGO encodes a protein with domains of tandem QH and QN repeats. Transcripts and promoter GUS reporter analyses indicated that RGO is expressed in roots, leaves, stems, floral and siliques tissues but not in seeds. Expression of the RGO:YFP fusion protein demonstrated that RGO is localized to the endoplasmic reticulum. MicroRNA mediated silencing of RGO resulted in severe reductions in vegetative and root growth, delayed flowering and reduced seed yield and viability, suggesting that RGO is essential for plant development. Conversely, ectopic overexpression of RGO resulted in enhanced vegetative growth including increased axillary bud formation and a 20% higher seed yield. Stable overexpression of RGO in Brassica napus also produced a similar increase in seed yield. Cytokinin (CK) response assays including root growth, green calli formation from excised hypocotyls and chlorophyll retention during dark-induced senescence suggest that one role of RGO is to mediate CK responses in plant development. These results suggest that RGO could be a target gene for increasing crop seed yields. One-sentence summary RGO , a novel gene from Arabidopsis, is essential for plant development, mediates CK signaling and increases seed yield in Arabidopsis and rapeseed when overexpressed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.220
Teacher spread0.195 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes2
Has abstractyes

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