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Record W3004982347 · doi:10.1016/j.cjco.2020.01.006

Single Right Coronary Artery Supplying the Entire Heart

2020· article· en· W3004982347 on OpenAlexaff
Naoto Fukunaga, Paakadinesh Thavendiranathan, Vivek Rao

Bibliographic record

VenueCJC Open · 2020
Typearticle
Languageen
FieldMedicine
TopicCoronary Artery Anomalies
Canadian institutionsUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsMedicineCardiologyRight coronary arteryInternal medicineBicuspid aortic valveArteryCircumflexInterventricular septumBicuspid valveStenosisAortic valveMyocardial infarctionCoronary angiographyVentricle

Abstract

fetched live from OpenAlex

A 60-year-old man with hypertension, hyperlipidemia, and noninsulin-dependent diabetes had been followed for bicuspid aortic valve disease. Transthoracic echocardiography revealed severe bicuspid aortic valve stenosis with mean and peak transvalvular gradients of 57 mm Hg and 80 mm Hg, respectively. He recently became symptomatic and was put forth for surgical consideration. Preoperative angiography demonstrated that the left anterior descending (LAD) artery arose from the right coronary artery (RCA) (Fig. 1A). This vessel traversed to the anterior interventricular groove and provided normal LAD circulation. The left circumflex (LCX) artery was a continuation of the ongoing posterolateral artery and proceeded superiorly along the posterior interventricular groove providing the obtuse marginal vessels (Fig. 1B and C). Coronary computed tomography confirmed that the entire coronary circulation arose from the RCA with the LAD originating from the RCA (Fig. 1D). The single coronary artery branched into 2 vessels, one taking a course similar to an RCA and the other becoming the LAD. The RCA branch traveled posteriorly along the atrioventricular groove, bifurcating into the posterolateral artery and an ongoing left coronary system along the left atrioventricular groove in the expected location of the LCX providing the marginal branches (Fig. 1E and F). At surgery, antegrade cardioplegia was given via the aortic root once to achieve cardiac arrest. The stenotic bicuspid aortic valve was replaced with a biological valve. The RCA and adjacent LAD orifices were seen at a reasonable height above the aortic annulus, permitting standard supra-annular valve implantation. Because the LAD was not running in the aortic wall, there was no surgical revision to any coronary artery. However, the course of this artery would have surgical implications if aortic root procedures, such as a Bentall, an aortic valve-sparing root, or a Ross procedure, had been contemplated. These procedures require mobilization and reimplantation of the coronary ostia, which may have been challenging in this case. His subsequent postoperative course was uneventful. A single coronary artery is an extremely rare congenital coronary artery anomaly in which only 1 coronary artery arises from the aorta to supply the entire heart. The prevalence is 0.02% to 0.06% based on angiography.1Desmet W. Vanhaecke J. Vrolix M. et al.Isolated single coronary artery: a review of 50000 consecutive coronary angiographies.Eur Heart J. 1992; 13: 1637-1640Crossref PubMed Scopus (226) Google Scholar This variance may be associated with congenital heart diseases and an increased risk of sudden death due to decreased myocardial perfusion.2Topaz O. Demarchena E.J. Perin E. et al.Anomalous coronary arteries: angiographic findings in 80 patients.Int J Cardiol. 1992; 34: 129-138Abstract Full Text PDF PubMed Scopus (209) Google Scholar The relationship between bicuspid aortic valves and single coronary artery is unclear; however, a case report has been published.3Zoltowska D.M. Agrawal Y. Thind G.S. Kalavakunta J.K. Single coronary artery with bicuspid aortic valve.BMJ Case Rep. 2018; 2018 (bcr2018225309)Google Scholar We have reported a rare case of bicuspid aortic valve stenosis associated with a coronary anomaly. Although routine aortic valve replacement was performed uneventfully in this case, the need for a more complicated root procedure (due to aneurysm, dissection, infection, or desire for a pulmonary autograft) would have been complicated by this anomaly. Because the entire coronary circulation is dependent on a single coronary orifice, any complications related to coronary reimplantation would have been poorly tolerated. This case illustrates the need for preoperative coronary angiography in patients undergoing aortic valve surgery, particularly if a root procedure is being contemplated. The authors have no funding sources to declare.

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How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.342
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.283
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes1
Has abstractyes

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