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Record W3005254274 · doi:10.1093/imamat/hxaa023

Stable asymmetric spike equilibria for the Gierer–Meinhardt model with a precursor field

2020· article· en· W3005254274 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueIMA Journal of Applied Mathematics · 2020
Typearticle
Languageen
FieldComputer Science
TopicNonlinear Dynamics and Pattern Formation
Canadian institutionsUniversity of British ColumbiaUniversity of British Columbia HospitalDalhousie University
Fundersnot available
KeywordsBifurcationPattern formationEigenvalues and eigenvectorsLinearizationReaction–diffusion systemBifurcation diagramSteady state (chemistry)Parameter spaceHopf bifurcationSpike (software development)Vector fieldPhysicsMathematicsNonlinear systemMathematical analysisStatistical physicsGeometryChemistry

Abstract

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Abstract Precursor gradients in a reaction-diffusion system are spatially varying coefficients in the reaction kinetics. Such gradients have been used in various applications, such as the head formation in the Hydra, to model the effect of pre-patterns and to localize patterns in various spatial regions. For the 1D Gierer–Meinhardt (GM) model, we show that a non-constant precursor gradient in the decay rate of the activator can lead to the existence of stable, asymmetric and two-spike patterns, corresponding to localized peaks in the activator of different heights. These stable, asymmetric patterns co-exist in the same parameter space as symmetric two-spike patterns. This is in contrast to a constant precursor case, for which asymmetric spike patterns are known to be unstable. Through a determination of the global bifurcation diagram of two-spike steady-state patterns, we show that asymmetric patterns emerge from a supercritical symmetry-breaking bifurcation along the symmetric two-spike branch as a parameter in the precursor field is varied. Through a combined analytical-numerical approach, we analyse the spectrum of the linearization of the GM model around the two-spike steady state to establish that portions of the asymmetric solution branches are linearly stable. In this linear stability analysis, a new class of vector-valued non-local eigenvalue problem is derived and analysed.

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Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.853
Threshold uncertainty score0.276

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.244
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it