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Record W3006197350 · doi:10.1149/1945-7111/ab6ff3

Review—Electrochemical Approaches and Advances towards the Detection of Drug Resistance

2020· article· en· W3006197350 on OpenAlexafffund
Rafiqul Islam, Huy Tran Le Luu, Sabine Kuss

Bibliographic record

VenueJournal of The Electrochemical Society · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsUniversity of Manitoba
FundersResearch Manitoba
KeywordsDrugNanotechnologyDrug resistanceElectrochemistryAntibioticsBiochemical engineeringMaterials scienceCombinatorial chemistryPharmacologyMedicineChemistryBiologyMicrobiologyEngineeringElectrode

Abstract

fetched live from OpenAlex

Drug resistance in bacteria and cancer is a growing problem that decreases drug treatment effectiveness and increases the severity of bacterial infections as well as cancer mortality. Due to their high sensitivity, low cost, and rapid analysis time, electrochemical methods have been increasingly employed to tackle this challenge throughout the last decade. This review covers literature on the electrochemical characterization of antibiotics and chemotherapeutic drugs, as well as advances in analyzing interactions between drug compounds and biological cells. Recent developments towards the quantitative detection of drug resistance in bacteria and cancer by electrochemistry are discussed, and the use of specialized electrochemical instrumentation, such as scanning electrochemical microscopy, is highlighted.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.614
Threshold uncertainty score0.276

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.244
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations37
Published2020
Admission routes2
Has abstractyes

Explore more

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